Protein: NECA2
N-terminal EF-hand calcium-binding protein 2 (EF-hand calcium-binding protein 2) (Neuronal calcium-binding protein 2) (Synaptotagmin-interacting protein 2) (Stip-2)

Gene: NECA2, NECAB2
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q7Z6G3

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0030424 - axon
GO:0030425 - dendrite

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1279939

NECA2
N-terminal EF-hand calcium-binding protein 2

5

4

High-throughput

0.939

High

1279949

NECA1
N-terminal EF-hand calcium-binding protein 1

4

4

High-throughput

0.902

High

1279979

NEK6
Serine/threonine-protein kinase Nek6

5

0

High-throughput

0.879

High

1279967

NECA3
N-terminal EF-hand calcium-binding protein 3

2

4

High-throughput

0.811

High

1224988

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

2

High-throughput

0.783

High

1279952

LNX1
E3 ubiquitin-protein ligase LNX

6

3

High-throughput

0.735

High

930736

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

0

High-throughput

0.702

High

1279981

RIC8A
Chaperone Ric-8A

1

0

High-throughput

0.702

High

1143382

PCM1
Pericentriolar material 1 protein

5

0

High-throughput

0.693

High

1028482

BEX3
Protein BEX3

3

1

High-throughput

0.675

High

1279983

KLC4
Kinesin light chain 4

3

1

High-throughput

0.675

High

1279978

SH24A
SH2 domain-containing protein 4A

4

0

High-throughput

0.668

High

140331

SDCB1
Syntenin-1

2

4

High-throughput

0.651

High

51364

SRCRL
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

3

0

High-throughput

0.646

High

1118901

BYST
Bystin

3

0

High-throughput

0.646

High

1279985

AIRIM
AFG2-interacting ribosome maturation factor

3

0

High-throughput

0.646

High

709251

AA2AR
Adenosine receptor A2a

2

1

Small-scale

0.639

High

1279964

MY15B
Unconventional myosin-XVB

1

0

High-throughput

0.630

High

900389

FXR2
RNA-binding protein FXR2

2

3

High-throughput

0.613

High

1279976

ISCU
Iron-sulfur cluster assembly enzyme ISCU

2

0

High-throughput

0.613

High

1158403

CDC37
Hsp90 co-chaperone Cdc37

2

1

High-throughput

0.606

High

1214514

ACBD5
Acyl-CoA-binding domain-containing protein 5

2

0

High-throughput

0.602

High

1279975

ZY11B
Protein zyg-11 homolog B

2

0

High-throughput

0.602

High

910965

IMA1
Importin subunit alpha-1

2

0

High-throughput

0.601

High

1279974

DGC6L
Protein DGCR6L

3

2

High-throughput

0.597

High

635085

CAN3
Calpain-3

1

0

High-throughput

0.589

High

1104206

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

2

0

High-throughput

0.580

High

1187236

PUS10
tRNA pseudouridine synthase Pus10

2

0

High-throughput

0.580

High

1279947

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

1279948

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

0

High-throughput

0.580

High

1279961

DTBP1
Dysbindin

2

0

High-throughput

0.580

High

1279968

MTMR9
Myotubularin-related protein 9

2

0

High-throughput

0.580

High

1279982

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1242669

KLC3
Kinesin light chain 3

1

1

High-throughput

0.573

High

1279973

BEX2
Protein BEX2

1

1

High-throughput

0.573

High

322842

MTCL2
Microtubule cross-linking factor 2

2

1

High-throughput

0.553

High

1150116

TCEA2
Transcription elongation factor A protein 2

2

2

High-throughput

0.553

High

1279965

F161B
Protein FAM161B

2

1

High-throughput

0.553

High

252100

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.549

High

1193096

DRC12
Dynein regulatory complex protein 12

1

0

High-throughput

0.549

High

1279954

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.549

High

1279966

ODAD4
Outer dynein arm-docking complex subunit 4

1

0

High-throughput

0.549

High

1279977

CARD9
Caspase recruitment domain-containing protein 9

1

0

High-throughput

0.549

High

900004

FXR1
RNA-binding protein FXR1

1

3

High-throughput

0.541

High

1056821

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.541

High

1185262

F161A
Protein FAM161A

1

1

High-throughput

0.523

High

1279955

TSC1
Hamartin

1

0

High-throughput

0.518

High

1105629

GOGA4
Golgin subfamily A member 4

1

0

High-throughput

0.513

High

1279950

INADL
InaD-like protein

1

3

High-throughput

0.481

High

835440

GRM5
Metabotropic glutamate receptor 5

1

1

Small-scale

0.479

High

63729

A5PKX9
INADL protein

1

3

High-throughput

0.470

High

130844

DFFA
DNA fragmentation factor subunit alpha

1

0

High-throughput

0.460

High

680928

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.460

High

1279399

CPEB2
Cytoplasmic polyadenylation element-binding protein 2

1

0

Small-scale

0.460

High

1279986

TBA8
Tubulin alpha-8 chain

1

0

High-throughput

0.460

High

1026112

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.458

High

404828

PRIO
Major prion protein

1

1

High-throughput

0.445

High

883396

INPP
Inositol polyphosphate 1-phosphatase

1

1

High-throughput

0.439

High

1120861

DGCR6
Protein DGCR6

1

2

High-throughput

0.439

High

106185

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1279992

X5DP20
DiGeorge syndrome critical region 6 isoform D

1

2

High-throughput

0.417

High

1279993

X5DP77
Inositol polyphosphate-1-phosphatase isoform A

1

1

High-throughput

0.417

High

1279963

NTAQ1
Protein N-terminal glutamine amidohydrolase

5

0

High-throughput

0.378

High

1055236

MTG8
Protein CBFA2T1

4

0

High-throughput

0.365

High

1279987

RCOR3
REST corepressor 3

4

0

High-throughput

0.365

High

1279943

CC146
Coiled-coil domain-containing protein 146

3

0

High-throughput

0.352

High

1279971

KIFC3
Kinesin-like protein KIFC3

3

0

High-throughput

0.352

High

1279988

DAXX
Death domain-associated protein 6

3

0

High-throughput

0.352

High

1279946

USBP1
Harmonin-binding protein USHBP1

3

0

High-throughput

0.345

High

246716

KDM1A
Lysine-specific histone demethylase 1A

3

0

High-throughput

0.341

High

1279944

TEX11
Testis-expressed protein 11

3

0

High-throughput

0.341

High

1276079

KANL1
KAT8 regulatory NSL complex subunit 1

2

0

High-throughput

0.330

High

1279970

CENPO
Centromere protein O

2

0

High-throughput

0.330

High

1208926

DCA10
DDB1- and CUL4-associated factor 10

2

0

High-throughput

0.328

High

65885

MSGN1
Mesogenin-1

2

0

High-throughput

0.316

High

217135

MS18B
Protein Mis18-beta

2

0

High-throughput

0.316

High

333362

SNAPN
SNARE-associated protein Snapin

2

0

High-throughput

0.316

High

1279941

MYPOP
Myb-related transcription factor, partner of profilin

2

0

High-throughput

0.316

High

1279942

TRI59
Tripartite motif-containing protein 59

2

0

High-throughput

0.316

High

1279951

CA216
UPF0500 protein C1orf216

2

0

High-throughput

0.316

High

1279953

CAGE1
Cancer-associated gene 1 protein

2

0

High-throughput

0.316

High

1279962

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.316

High

1279969

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.316

High

1279984

INT10
Integrator complex subunit 10

2

0

High-throughput

0.316

High

1279989

CS025
UPF0449 protein C19orf25

2

0

High-throughput

0.316

High

1063969

ECHP
Peroxisomal bifunctional enzyme

2

0

High-throughput

0.311

High

63304

ODAD3
Outer dynein arm-docking complex subunit 3

1

0

High-throughput

0.299

High

389846

TTHY
Transthyretin

1

0

High-throughput

0.299

High

1096577

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.299

High

1279957

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.299

High

1279959

GCC1
GRIP and coiled-coil domain-containing protein 1

1

0

High-throughput

0.299

High

1279960

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.299

High

1279990

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

0

High-throughput

0.299

High

185207

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.292

High

1063382

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.292

High

1279958

EAF2
ELL-associated factor 2

1

0

High-throughput

0.292

High

1279991

EMIL1
EMILIN-1

1

0

High-throughput

0.292

High

903192

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

0

High-throughput

0.282

High

621676

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.265

Low

1256684

CC121
Coiled-coil domain-containing protein 121

1

0

High-throughput

0.265

Low

1279956

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.265

Low

61957

GTPBA
GTP-binding protein 10

1

0

High-throughput

0.251

Low

239593

MED14
Mediator of RNA polymerase II transcription subunit 14

1

0

High-throughput

0.251

Low

297005

CCNK
Cyclin-K

1

0

High-throughput

0.251

Low

1279945

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

1279972

NOC4L
Nucleolar complex protein 4 homolog

1

0

High-throughput

0.251

Low

1279980

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

1

0

High-throughput

0.251

Low

1279940

ATL2
ADAMTS-like protein 2

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025