HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: EMC2 (Q15006)
ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35)
Gene: EMC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27342126, 31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 297
+	Hs
		925286 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		436308 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		951003 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		894020 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		545386 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		892379 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		915684 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		120444 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00
+	Hs
		915796 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		TTC7B_HUMAN (28-190): 1.86e-47: 171: 23.98
+	Hs
		672803 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		CDC27_HUMAN (34-294): 4.44e-33: 130: 15.27
+	Hs
		900614 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		TMTC3_HUMAN (102-296): 1.43e-23: 102: 11.96
+	Hs
		925380 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		TMTC3_HUMAN (102-296): 1.43e-23: 102: 11.96
+	Hs
		915775 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		TMTC3_HUMAN (102-296): 1.43e-23: 102: 11.96
+	Hs
		120504 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		TMTC3_HUMAN (102-296): 1.43e-23: 102: 11.96