HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: ARL8B (Q9NVJ2)
ADP-ribosylation factor-like protein 8B (EC 3.6.5.2) (ADP-ribosylation factor-like protein 10C) (Novel small G protein indispensable for equal chromosome segregation 1)
Gene: ARL8B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0030496 - midbody and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 186
+	Hs
		925186 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ARF5_HUMAN (1-184): 8.82e-84: 246: 30.44
+	Hs
		912848 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ARF6_HUMAN (12-183): 2.69e-84: 248: 34.88
+	Hs
		900355 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RAB1A_HUMAN (5-185): 3.36e-69: 210: 22.16
+	Hs
		918847 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RAB1A_HUMAN (5-185): 3.36e-69: 210: 22.16
+	Hs
		900882 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RAB1B_HUMAN (21-185): 4.49e-68: 207: 23.08
+	Hs
		925600 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RAB1B_HUMAN (21-185): 4.49e-68: 207: 23.08
+	Hs
		436244 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		RAB1A_HUMAN (5-185): 3.36e-69: 210: 22.16
+	Hs
		436535 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		ARL8B_HUMAN (1-186): 2.68e-69: 210: 100.00
+	Hs
		918849 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		RAB1A_HUMAN (5-185): 3.36e-69: 210: 22.16
+	Hs
		951391 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ARL8B_HUMAN (1-186): 2.68e-69: 210: 100.00
+	Hs
		436498 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		RAB1B_HUMAN (21-185): 4.49e-68: 207: 23.08
+	Hs
		893872 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		RAB1A_HUMAN (5-185): 3.36e-69: 210: 22.16
+	Hs
		894498 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ARL8B_HUMAN (1-186): 2.68e-69: 210: 100.00
+	Hs
		894409 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		RAB1B_HUMAN (21-185): 4.49e-68: 207: 23.08
+	Hs
		895022 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RAB2A_HUMAN (21-184): 1.91e-64: 198: 16.67
+	Hs
		895028 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RAB2A_HUMAN (21-184): 1.91e-64: 198: 16.67
+	Hs
		436232 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		RAB2A_HUMAN (21-184): 1.91e-64: 198: 16.67
+	Hs
		895037 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		RAB2A_HUMAN (21-184): 1.91e-64: 198: 16.67
+	Hs
		893849 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		RAB2A_HUMAN (21-184): 1.91e-64: 198: 16.67
+	Hs
		545297 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		RAB2A_HUMAN (21-184): 1.91e-64: 198: 16.67