HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: RAI14 (Q9P0K7)
Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14)
Gene: RAI14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras, Ank_4~Ras
Common GO terms	GO:0005829 - cytosol GO:0005938 - cell cortex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 980
+	Hs
		925681 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RAI14_HUMAN (1-980): 4.28e-77: 274: 100.00
+	Hs
		900754 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		951418 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		RAI14_HUMAN (1-980): 4.28e-77: 274: 100.00
+	Hs
		925488 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		900896 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		Q9H4D1_HUMAN (11-256): 9.8e-49: 188: 24.29
+	Hs
		900423 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ANK3_HUMAN (24-405): 2.11e-47: 187: 18.74
+	Hs
		925238 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ANK3_HUMAN (24-405): 2.11e-47: 187: 18.74
+	Hs
		950953 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ANK3_HUMAN (24-405): 2.11e-47: 187: 18.74
+	Hs
		883465 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RIPK4_HUMAN (4-181): 1.95e-43: 172: 30.73
+	Hs
		951304 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		UACA_HUMAN (411-974): 2.3e-39: 161: 24.63
+	Hs
		900403 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		925219 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		925423 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		HACE1_HUMAN (26-174): 1.39e-13: 77.4: 33.56
+	Hs
		436267 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		901042 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		KDIS_HUMAN (160-403): 1.98e-12: 73.9: 16.39
+	Hs
		950942 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		893926 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		NOTC2_HUMAN (10-123): 1.42e-14: 81.1: 22.61
+	Hs
		925723 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		KDIS_HUMAN (160-403): 1.98e-12: 73.9: 16.39
+	Hs
		436568 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		KDIS_HUMAN (160-403): 1.98e-12: 73.9: 16.39
+	Hs
		951454 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		KDIS_HUMAN (160-403): 1.98e-12: 73.9: 16.39