HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: VANG2 (Q9ULK5)
Vang-like protein 2 (Loop-tail protein 1 homolog) (Strabismus 1) (Van Gogh-like protein 2)
Gene: VANGL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0060071 - Wnt signaling pathway, planar cell polarity pathway
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 521
+	Hs
		900711 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		925451 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		436415 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		951170 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		894231 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		545509 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		892496 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		915849 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		120550 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		VANG1_HUMAN (21-521): 0: 780: 72.87
+	Hs
		925726 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		436571 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		951456 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		894582 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		545698 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		892679 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		916071 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		VANG2_HUMAN (1-521): 0: 725: 100.00
+	Hs
		120711 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		VANG2_HUMAN (1-521): 0: 725: 100.00