HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: TRRAP (Q9Y4A5)
Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)
Gene: TRRAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31871319, 35906200
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~Ras
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 3859
+	Hs
		894617 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		545716 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		787450 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		787456 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		545244 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		900371 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Hs
		120332 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		893894 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Hs
		893980 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ATR_HUMAN (2569-3859): 0: 704: 15.07