Protein: RCC2
Protein RCC2 (RCC1-like protein TD-60) (Telophase disk protein of 60 kDa)

Gene: RCC2
Organism: Homo sapiens
Interactions: 175
UniProt ID: Q9P258

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

578488

RCC1
Regulator of chromosome condensation

1

13

High-throughput

0.618

High

592042

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.618

High

894538

CDC42
Cell division control protein 42 homolog

1

4

Small-scale

0.618

High

919291

RAN
GTP-binding nuclear protein Ran

1

7

High-throughput

0.618

High

925691

RAC1
Ras-related C3 botulinum toxin substrate 1

1

4

Small-scale

0.618

High

884606

RAB25
Ras-related protein Rab-25

1

0

High-throughput

0.586

High

228941

PRKN
E3 ubiquitin-protein ligase parkin

2

17

High-throughput

0.584

High

918743

H2B1C
Histone H2B type 1-C/E/F/G/I

2

4

High-throughput

0.584

High

999159

EP300
Histone acetyltransferase p300

2

7

High-throughput

0.584

High

331099

PAK4
Serine/threonine-protein kinase PAK 4

2

1

Small-scale

0.571

High

370603

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

1234572

SH2D3
SH2 domain-containing protein 3C

2

6

High-throughput

0.571

High

1291593

OTUB1
Ubiquitin thioesterase OTUB1

2

2

High-throughput

0.571

High

507517

ERG
Transcriptional regulator ERG

1

2

Small-scale

0.561

High

1350066

COR1C
Coronin-1C

1

4

Small-scale

0.561

High

157088

AIM2
Interferon-inducible protein AIM2

1

3

High-throughput

0.536

High

363331

FINC
Fibronectin

1

4

High-throughput

0.536

High

537673

NCF1
Neutrophil cytosol factor 1

1

1

High-throughput

0.536

High

575864

VINC
Vinculin

1

1

High-throughput

0.536

High

599740

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

4

High-throughput

0.536

High

718263

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.536

High

850993

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.536

High

1075543

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

1

High-throughput

0.536

High

1086005

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.536

High

1331027

DEFI6
Differentially expressed in FDCP 6 homolog

1

5

High-throughput

0.536

High

780239

CCNF
Cyclin-F

1

8

High-throughput

0.515

High

1350069

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

263857

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.501

High

890872

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.501

High

1273936

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

4

High-throughput

0.501

High

1206129

MYLK4
Myosin light chain kinase family member 4

1

3

High-throughput

0.489

High

1334035

WDR76
WD repeat-containing protein 76

1

11

High-throughput

0.489

High

119547

LEG9
Galectin-9

1

2

High-throughput

0.479

High

125767

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

7

High-throughput

0.479

High

245039

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.479

High

256117

OBSL1
Obscurin-like protein 1

1

5

High-throughput

0.479

High

298849

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

323238

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

339066

EGFR
Epidermal growth factor receptor

1

5

High-throughput

0.479

High

348108

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

354589

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

4

High-throughput

0.479

High

379971

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.479

High

385636

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.479

High

387642

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

442560

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

487802

ANDR
Androgen receptor

1

11

Small-scale

0.479

High

587035

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.479

High

641960

U2AF2
Splicing factor U2AF 65 kDa subunit

1

6

High-throughput

0.479

High

685068

STIP1
Stress-induced-phosphoprotein 1

1

10

High-throughput

0.479

High

719642

MERL
Merlin

1

2

High-throughput

0.479

High

742574

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

772188

VHL
von Hippel-Lindau disease tumor suppressor

1

2

High-throughput

0.479

High

809462

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

Small-scale

0.479

High

836045

GSK3B
Glycogen synthase kinase-3 beta

1

5

High-throughput

0.479

High

850219

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

9

High-throughput

0.479

High

880838

HDAC4
Histone deacetylase 4

1

9

High-throughput

0.479

High

909257

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.479

High

913156

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

918059

H4
Histone H4

1

1

High-throughput

0.479

High

932421

ACTC
Actin, alpha cardiac muscle 1

1

3

High-throughput

0.479

High

934529

CSK21
Casein kinase II subunit alpha

1

8

High-throughput

0.479

High

1021174

FOXC1
Forkhead box protein C1

1

6

High-throughput

0.479

High

1030525

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.479

High

1032658

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.479

High

1036160

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1043624

CUL4B
Cullin-4B

1

15

High-throughput

0.479

High

1061656

CUL7
Cullin-7

1

6

High-throughput

0.479

High

1064220

TNIP1
TNFAIP3-interacting protein 1

1

10

High-throughput

0.479

High

1064792

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1127535

DOC11
Dedicator of cytokinesis protein 11

1

2

Small-scale

0.479

High

1136337

RC3H1
Roquin-1

1

2

High-throughput

0.479

High

1200710

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

1201731

ZCH18
Zinc finger CCCH domain-containing protein 18

1

4

High-throughput

0.479

High

1221794

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

1222615

SLX4
Structure-specific endonuclease subunit SLX4

1

5

High-throughput

0.479

High

1233555

MINK1
Misshapen-like kinase 1

1

5

High-throughput

0.479

High

1241044

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1243563

CSK23
Casein kinase II subunit alpha 3

1

8

High-throughput

0.479

High

1244540

NUP43
Nucleoporin Nup43

1

8

High-throughput

0.479

High

1246188

COP1
E3 ubiquitin-protein ligase COP1

1

14

High-throughput

0.479

High

1251934

RIN3
Ras and Rab interactor 3

1

2

High-throughput

0.479

High

1267205

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1272659

CSN5
COP9 signalosome complex subunit 5

1

6

High-throughput

0.479

High

1288357

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

8

High-throughput

0.479

High

1292267

AURKB
Aurora kinase B

1

4

Small-scale

0.479

High

1294088

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1304948

NECD
Necdin

1

3

High-throughput

0.479

High

1318516

TRI31
E3 ubiquitin-protein ligase TRIM31

1

2

High-throughput

0.479

High

1319099

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

20

High-throughput

0.479

High

1327794

RGAP1
Rac GTPase-activating protein 1

1

5

Small-scale

0.479

High

1328276

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

1330530

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

1331500

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

1333775

ECT2
Protein ECT2

1

2

High-throughput

0.479

High

1342807

BRD7
Bromodomain-containing protein 7

1

8

High-throughput

0.479

High

1343731

ANLN
Anillin

1

2

High-throughput

0.479

High

1344511

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

1347295

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

1347385

PK1IP
p21-activated protein kinase-interacting protein 1

1

11

Small-scale

0.479

High

1349587

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

1

High-throughput

0.479

High

1350059

MBD5
Methyl-CpG-binding domain protein 5

1

3

High-throughput

0.479

High

1350061

HDAC6
Histone deacetylase 6

1

9

High-throughput

0.479

High

1350063

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1350064

TNIK
TRAF2 and NCK-interacting protein kinase

1

5

High-throughput

0.479

High

1350067

FZR1
Fizzy-related protein homolog

1

6

High-throughput

0.479

High

1350068

FAF1
FAS-associated factor 1

1

3

High-throughput

0.479

High

1350071

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

1

High-throughput

0.479

High

1350072

TRAF6
TNF receptor-associated factor 6

1

4

High-throughput

0.479

High

340544

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.458

High

352716

TNFA
Tumor necrosis factor

1

0

High-throughput

0.458

High

617912

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.458

High

625623

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

813802

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

881048

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

899069

PSME3
Proteasome activator complex subunit 3

1

0

Small-scale

0.458

High

1053678

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.458

High

1121634

BOREA
Borealin

1

0

Small-scale

0.458

High

1159311

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1310533

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

1328909

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1350062

TRM7
tRNA

1

0

High-throughput

0.458

High

402564

JUN
Transcription factor Jun

1

4

High-throughput

0.445

High

497709

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

581879

VCAM1
Vascular cell adhesion protein 1

1

4

High-throughput

0.445

High

875380

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

924915

GRB2
Growth factor receptor-bound protein 2

1

6

High-throughput

0.445

High

1057695

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

1318876

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

1328054

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

14

High-throughput

0.445

High

1330651

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

14

High-throughput

0.445

High

1334582

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.445

High

233666

NUPR1
Nuclear protein 1

1

1

High-throughput

0.437

High

295341

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.437

High

553933

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

570134

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.437

High

652472

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

721651

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

781235

ETV3
ETS translocation variant 3

1

2

High-throughput

0.437

High

832750

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.437

High

903569

WDR5
WD repeat-containing protein 5

1

5

High-throughput

0.437

High

935319

H31
Histone H3.1

1

6

High-throughput

0.437

High

1018198

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

6

High-throughput

0.437

High

1086336

H31T
Histone H3.1t

1

6

High-throughput

0.437

High

1148522

DUS29
Dual specificity phosphatase 29

1

2

High-throughput

0.437

High

1172064

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1176273

ASXL2
Putative Polycomb group protein ASXL2

1

5

High-throughput

0.437

High

1220827

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.437

High

1239175

ZBT38
Zinc finger and BTB domain-containing protein 38

1

2

Small-scale

0.437

High

1269803

ESR2
Estrogen receptor beta

1

11

High-throughput

0.437

High

1288102

OTUB2
Ubiquitin thioesterase OTUB2

1

2

Small-scale

0.437

High

1288486

MBD6
Methyl-CpG-binding domain protein 6

1

5

High-throughput

0.437

High

1300970

CIC
Protein capicua homolog

1

4

High-throughput

0.437

High

1319309

ASXL3
Putative Polycomb group protein ASXL3

1

5

High-throughput

0.437

High

1330870

Q9H4D1
Protein kinase

1

4

High-throughput

0.437

High

1348292

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1350060

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

2

High-throughput

0.437

High

1350065

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

High-throughput

0.437

High

1149

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.426

High

529834

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

831749

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

883661

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

5

High-throughput

0.407

High

376325

ANXA1
Annexin A1

1

0

Small-scale

0.391

High

949068

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

1293143

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

1302603

INT14
Integrator complex subunit 14

1

0

High-throughput

0.279

Low

182934

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

242145

PAGE4
P antigen family member 4

1

0

High-throughput

0.249

Low

1126694

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

1260936

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

1314407

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low

1345442

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.249

Low

1350070

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

1350073

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.249

Low

1169473

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

1242799

DIK2A
Divergent protein kinase domain 2A

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024