HitPredict

Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Interactor 2: CHM2B (Q9UQN3)
Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2)
Gene: CHMP2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0007032 - endosome organization GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 213
+	Hs
		221841 RAB5C_HUMAN (1-216): 8.5e-93: 272: 100.00		CHM2A_HUMAN (3-188): 1.88e-37: 131: 32.80
+	Hs
		221847 RB11A_HUMAN (12-216): 1.17e-86: 256: 39.25		CHM2A_HUMAN (3-188): 1.88e-37: 131: 32.80
+	Hs
		901059 RAB5C_HUMAN (1-216): 8.5e-93: 272: 100.00		CHM1A_HUMAN (14-210): 2.02e-30: 112: 17.26
+	Hs
		900982 RAB5C_HUMAN (1-216): 8.5e-93: 272: 100.00		CHM4C_HUMAN (7-198): 6.05e-29: 109: 18.04
+	Hs
		976686 RB11A_HUMAN (12-216): 1.17e-86: 256: 39.25		CHMP3_HUMAN (1-211): 9.12e-34: 122: 25.23
+	Hs
		901040 RAB5C_HUMAN (1-216): 8.5e-93: 272: 100.00		CHM4B_HUMAN (8-200): 6.08e-23: 94: 21.89
+	Hs
		976365 RB11A_HUMAN (12-216): 1.17e-86: 256: 39.25		CHM1B_HUMAN (14-210): 5.03e-29: 109: 18.27
+	Hs
		1430472 RAB1B_HUMAN (14-214): 2.66e-89: 262: 40.30		CHM4B_HUMAN (8-200): 6.08e-23: 94: 21.89
+	Hs
		1155390 RB11B_HUMAN (12-216): 8.73e-86: 254: 38.89		CHM4B_HUMAN (8-200): 6.08e-23: 94: 21.89