Protein: CHM2A
Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1)

Gene: CHM2A, CHMP2A
Organism: Homo sapiens
Interactions: 87
UniProt ID: O43633

Gene Ontology (top 5):
GO:0000421 - autophagosome membrane
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0000815 - ESCRT III complex
GO:0001778 - plasma membrane repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

221896

CHMP3
Charged multivesicular body protein 3

5

19

Small-scale

0.926

High

221886

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

3

8

Small-scale

0.861

High

221888

CHMP5
Charged multivesicular body protein 5

2

19

High-throughput

0.811

High

221882

CHM4B
Charged multivesicular body protein 4b

2

20

Small-scale

0.799

High

221824

STABP
STAM-binding protein

5

9

Small-scale

0.720

High

221872

MITD1
MIT domain-containing protein 1

3

2

High-throughput

0.667

High

221893

VPS4A
Vacuolar protein sorting-associated protein 4A

3

20

Small-scale

0.664

High

221818

CHM2A
Charged multivesicular body protein 2a

1

17

High-throughput

0.656

High

221877

MIA2
Melanoma inhibitory activity protein 2

3

1

High-throughput

0.640

High

221887

SIX2
Homeobox protein SIX2

2

2

High-throughput

0.628

High

221862

CHM1B
Charged multivesicular body protein 1b

1

19

High-throughput

0.618

High

221885

CHM1A
Charged multivesicular body protein 1a

1

19

High-throughput

0.618

High

221857

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

2

0

High-throughput

0.602

High

221878

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

3

High-throughput

0.601

High

221856

E2F4
Transcription factor E2F4

2

0

High-throughput

0.588

High

123948

SNP23
Synaptosomal-associated protein 23

2

0

High-throughput

0.585

High

221892

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

2

1

High-throughput

0.584

High

221870

DOCK8
Dedicator of cytokinesis protein 8

1

0

High-throughput

0.549

High

221822

RENR
Renin receptor

1

1

High-throughput

0.536

High

221828

CLCA
Clathrin light chain A

1

3

High-throughput

0.536

High

221829

CLCB
Clathrin light chain B

1

3

High-throughput

0.536

High

221836

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

221840

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.536

High

221841

RAB5C
Ras-related protein Rab-5C

1

5

High-throughput

0.536

High

221842

RAB7A
Ras-related protein Rab-7a

1

8

High-throughput

0.536

High

221845

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.536

High

221852

SMAD4
Mothers against decapentaplegic homolog 4

1

3

High-throughput

0.536

High

221853

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.536

High

221863

MILR1
Allergin-1

1

2

High-throughput

0.536

High

221873

TFG
Protein TFG

1

4

High-throughput

0.536

High

221881

UN45A
Protein unc-45 homolog A

1

2

High-throughput

0.536

High

221889

SPAST
Spastin

1

20

High-throughput

0.536

High

221830

TGFB3
Transforming growth factor beta-3 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.518

High

171956

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

2

High-throughput

0.515

High

221839

HD
Huntingtin

1

1

High-throughput

0.515

High

194635

CLD3
Claudin-3

1

0

High-throughput

0.513

High

221819

MYO1B
Unconventional myosin-Ib

1

0

High-throughput

0.513

High

221848

TXN4A
Thioredoxin-like protein 4A

1

0

High-throughput

0.513

High

221864

SNX32
Sorting nexin-32

1

0

High-throughput

0.513

High

221883

BCDO1
Beta,beta-carotene 15,15'-dioxygenase

1

0

High-throughput

0.513

High

221850

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

2

High-throughput

0.508

High

221875

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

Small-scale

0.504

High

221838

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

6

Small-scale

0.501

High

221867

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.489

High

221895

RT18C
Small ribosomal subunit protein bS18m

1

1

High-throughput

0.489

High

221821

VPS4B
Vacuolar protein sorting-associated protein 4B

1

20

Small-scale

0.481

High

221837

SYUA
Alpha-synuclein

1

3

High-throughput

0.481

High

172294

XPO1
Exportin-1

1

5

High-throughput

0.479

High

221826

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

221827

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

221833

BTF3
Transcription factor BTF3

1

4

High-throughput

0.479

High

221844

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

221851

TADBP
TAR DNA-binding protein 43

1

2

Small-scale

0.479

High

221868

CGAS
Cyclic GMP-AMP synthase

1

3

High-throughput

0.479

High

221890

SEC63
Translocation protein SEC63 homolog

1

3

High-throughput

0.479

High

221897

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

6

Small-scale

0.479

High

133710

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

221831

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

221834

CD9
CD9 antigen

1

0

High-throughput

0.458

High

221843

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

0

High-throughput

0.458

High

221846

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.458

High

221849

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.458

High

221855

TWST1
Twist-related protein 1

1

0

High-throughput

0.458

High

221869

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

221876

SH3K1
SH3 domain-containing kinase-binding protein 1

1

0

Small-scale

0.458

High

221884

SPCS
O-phosphoseryl-tRNA(Sec) selenium transferase

1

0

High-throughput

0.458

High

221891

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.458

High

221861

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

4

Small-scale

0.457

High

221847

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.457

High

221858

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

1

1

High-throughput

0.457

High

221871

TP4AP
Short transient receptor potential channel 4-associated protein

1

1

High-throughput

0.457

High

221898

TNPO3
Transportin-3

1

5

High-throughput

0.457

High

221820

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.445

High

221854

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.445

High

221860

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

221832

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.426

High

221874

OSTF1
Osteoclast-stimulating factor 1

2

0

High-throughput

0.328

High

221894

TRI35
E3 ubiquitin-protein ligase TRIM35

2

0

High-throughput

0.328

High

221879

CINP
Cyclin-dependent kinase 2-interacting protein

2

0

High-throughput

0.313

High

221825

RPP29
Ribonuclease P protein subunit p29

1

0

High-throughput

0.279

Low

221859

FAH2B
Oxaloacetate tautomerase FAHD2B, mitochondrial

1

0

High-throughput

0.279

Low

221865

CCD83
Coiled-coil domain-containing protein 83

1

0

High-throughput

0.279

Low

221823

NOL4
Nucleolar protein 4

1

0

High-throughput

0.265

Low

221835

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

221866

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low

221880

GO45
Golgin-45

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025