HitPredict

Interactor 1: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Interactor 2: RGPA1 (Q6GYQ0)
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)
Gene: RALGAPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap_GAP~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 244 Hs			1 2036
+	Hs
		1151769 RND1_HUMAN (1-244): 1.22e-90: 268: 58.20		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		915756 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		894131 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		925359 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		900583 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		915714 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		RGPA2_HUMAN (1-2030): 0: 2671: 49.46
+	Hs
		852540 RND2_HUMAN (20-244): 3.9e-103: 300: 64.00		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		196428 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		SI1L1_HUMAN (1683-2015): 2.28e-106: 380: 19.22
+	Hs
		916041 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		SI1L2_HUMAN (1694-2016): 4.06e-106: 379: 18.88
+	Hs
		925514 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91
+	Hs
		915799 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		900790 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91
+	Hs
		230232 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Hs
		894180 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		835036 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		TSC2_HUMAN (1727-2033): 1.18e-96: 349: 23.90
+	Hs
		925407 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		900651 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		230233 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Dm
		776929 RAC1_DROME (24-211): 4.19e-77: 232: 42.02		X2JDH0_DROME (1637-2013): 4.12e-102: 367: 21.16
+	Dm
		776932 RAC1_DROME (24-211): 4.19e-77: 232: 42.02		X2JJU0_DROME (1637-2013): 3.69e-102: 367: 21.16