HitPredict

Interactor 1: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Interactor 2: NECT3 (Q9NQS3)
Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113)
Gene: NECTIN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 244 Hs			1 549
+	Hs
		852637 RND2_HUMAN (20-244): 3.9e-103: 300: 64.00		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		436527 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		1269232 RND1_HUMAN (1-244): 1.22e-90: 268: 58.20		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		915999 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		852588 RND2_HUMAN (20-244): 3.9e-103: 300: 64.00		KIRR1_HUMAN (41-509): 3.57e-62: 219: 17.59
+	Hs
		852576 RND2_HUMAN (20-244): 3.9e-103: 300: 64.00		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		436458 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		KIRR1_HUMAN (41-509): 3.57e-62: 219: 17.59
+	Hs
		1269204 RND1_HUMAN (1-244): 1.22e-90: 268: 58.20		KIRR1_HUMAN (41-509): 3.57e-62: 219: 17.59
+	Hs
		436439 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		915896 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		KIRR1_HUMAN (41-509): 3.57e-62: 219: 17.59
+	Hs
		915877 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		530163 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		NCAM1_HUMAN (2-511): 1.22e-57: 208: 12.43
+	Hs
		852702 RND2_HUMAN (20-244): 3.9e-103: 300: 64.00		ROBO1_HUMAN (264-548): 5.78e-25: 112: 10.39
+	Hs
		915725 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		SDK2_HUMAN (39-476): 2.32e-34: 140: 12.92
+	Hs
		915792 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		SDK1_HUMAN (5-499): 7.02e-34: 139: 13.50
+	Hs
		436602 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		ROBO1_HUMAN (264-548): 5.78e-25: 112: 10.39
+	Hs
		1269269 RND1_HUMAN (1-244): 1.22e-90: 268: 58.20		ROBO1_HUMAN (264-548): 5.78e-25: 112: 10.39
+	Hs
		916112 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		ROBO1_HUMAN (264-548): 5.78e-25: 112: 10.39
+	Hs
		915989 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		ROBO2_HUMAN (264-503): 6.31e-25: 111: 12.11
+	Ce
		136800 RHO1_CAEEL (22-200): 2.46e-93: 274: 50.28		UNC89_CAEEL (69-289): 2.15e-12: 72.4: 8.60