HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: VPS35 (Q96QK1)
Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35)
Gene: VPS35

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.689

The method score is based on:

Property Details
Experiments 35271311, 24344282, 34432599, 40437099
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005770 - late endosome
GO:0005829 - cytosol
GO:0010008 - endosome membrane
and 5 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 207
Hs

1 796
+ Mm
+ Dm
+ Mm
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025