Protein: VPS35
Vacuolar protein sorting-associated protein 35 (Vacuolar protein-targeting protein 7)

Gene: VPS35
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: P34110

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0005768 - endosome
GO:0005770 - late endosome
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

757372

VPS29
Vacuolar protein sorting-associated protein 29

12

6

Small-scale

0.981

High

757379

PEP8
Carboxypeptidase Y-deficient protein 8

11

9

Small-scale

0.974

High

757365

VPS35
Vacuolar protein sorting-associated protein 35

3

1

Small-scale

0.854

High

757399

VPS5
Vacuolar protein sorting-associated protein 5

14

4

Small-scale

0.762

High

748253

VPS17
Vacuolar protein sorting-associated protein 17

8

0

Small-scale

0.718

High

757382

ATG18
Autophagy-related protein 18

3

0

Small-scale

0.640

High

748721

YPT7
Ypt/Rab-type GTPase YPT7

2

4

Small-scale

0.619

High

733798

VPS10
Vacuolar protein sorting/targeting protein VPS10

2

2

Small-scale

0.614

High

757381

MVP1
Sorting nexin MVP1

2

9

High-throughput

0.613

High

757376

ATC2
Calcium-transporting ATPase 2

2

1

High-throughput

0.608

High

757390

MUK1
Protein MUK1

2

0

Small-scale

0.605

High

526318

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.571

High

544353

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.571

High

757395

ATG9
Autophagy-related protein 9

2

1

Small-scale

0.566

High

757388

VPS9
Vacuolar protein sorting-associated protein 9

1

1

Small-scale

0.552

High

757378

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

757387

ATG2
Autophagy-related protein 2

1

0

Small-scale

0.529

High

757370

FTH1
Iron transporter FTH1

1

0

High-throughput

0.518

High

757391

SNA4
Protein SNA4

1

0

High-throughput

0.518

High

721818

XPO1
Exportin-1

1

1

High-throughput

0.489

High

757394

YTM1
Ribosome biogenesis protein YTM1

1

1

High-throughput

0.489

High

523517

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.479

High

579140

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

672638

BPH1
Beige protein homolog 1

1

1

High-throughput

0.479

High

757369

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

757392

SNX3
Sorting nexin-3

1

8

Small-scale

0.479

High

757375

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

359192

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.458

High

757377

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

757386

BTN2
Protein BTN2

1

0

Small-scale

0.458

High

757393

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.458

High

392504

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

444479

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.437

High

675873

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

757373

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

757371

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

1

High-throughput

0.407

High

757383

ERJ5
ER-localized J domain-containing protein 5

1

2

High-throughput

0.407

High

712774

CHS3
Chitin synthase 3

2

0

Small-scale

0.310

High

757380

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

571818

SNA3
Protein SNA3

1

0

High-throughput

0.282

High

748815

SWE1
Mitosis inhibitor protein kinase SWE1

1

0

High-throughput

0.279

Low

757367

NNK1
Nitrogen network kinase 1

1

0

High-throughput

0.279

Low

757384

YMR1
Phosphoinositide 3-phosphatase

1

0

High-throughput

0.279

Low

757389

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.279

Low

757368

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.269

Low

757374

TRM5
tRNA

1

0

High-throughput

0.269

Low

583159

CUP2
Transcriptional activator protein CUP2

1

0

High-throughput

0.265

Low

506443

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

706686

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

757366

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

757396

APC11
Anaphase-promoting complex subunit 11

1

0

High-throughput

0.249

Low

757398

GIS3
Protein GIS3

1

0

High-throughput

0.249

Low

577086

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.232

Low

757385

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

757397

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025