HitPredict

Interactor 1: STXB1 (P61764)
Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67)
Gene: STXBP1

Interactor 2: GPC5B (Q9NZH0)
G-protein coupled receptor family C group 5 member B (A-69G12.1) (Retinoic acid-induced gene 2 protein) (RAIG-2)
Gene: GPRC5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 594 Hs			1 403
+	Mm
		139557 STXB1_MOUSE (1-594): 0: 680: 100.00		GRM5_MOUSE (30-403): 1.24e-89: 295: 17.16
+	Mm
		139567 STXB1_MOUSE (1-594): 0: 680: 100.00		GRM7_MOUSE (30-363): 2.2e-88: 288: 15.68
+	Mm
		139568 STXB1_MOUSE (1-594): 0: 680: 100.00		GRM4_MOUSE (30-362): 1.33e-82: 272: 15.72
+	Hs
		119673 STXB3_HUMAN (1-593): 0: 584: 50.59		GPC5B_HUMAN (1-403): 3.08e-124: 366: 100.00
+	Hs
		1261656 SCFD1_HUMAN (4-588): 8.01e-163: 481: 14.62		GPC5B_HUMAN (1-403): 3.08e-124: 366: 100.00
+	Hs
		119672 STXB3_HUMAN (1-593): 0: 584: 50.59		GPC5D_HUMAN (44-373): 5.33e-59: 197: 33.23
+	Hs
		1345169 VPS45_HUMAN (12-582): 5.03e-154: 456: 17.81		GPC5D_HUMAN (44-373): 5.33e-59: 197: 33.23