HitPredict

Interactor 1: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Interactor 2: KLRD1 (Q13241)
Natural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94)
Gene: KLRD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	18448674, 18083576
Identification Methods	x-ray crystallography, surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~Lectin_C
Common GO terms	GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 119 Hs			1 179
+	Hs
		488205 HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66		KLRD1_HUMAN (1-179): 2.95e-46: 151: 100.00
+	Hs
		354435 HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66		KLRD1_HUMAN (1-179): 2.95e-46: 151: 100.00
+	Hs
		382490 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		CLC4D_HUMAN (2-175): 1.43e-42: 143: 19.15
+	Hs
		488317 HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66		CLC4D_HUMAN (2-175): 1.43e-42: 143: 19.15
+	Hs
		382561 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		CLC4A_HUMAN (16-179): 3.06e-41: 140: 22.29
+	Hs
		382559 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		CLC4E_HUMAN (1-176): 8.25e-41: 138: 17.02
+	Hs
		488421 HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66		CLC4A_HUMAN (16-179): 3.06e-41: 140: 22.29
+	Hs
		488420 HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66		CLC4E_HUMAN (1-176): 8.25e-41: 138: 17.02
+	Hs
		674001 HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00		CLC4A_HUMAN (16-179): 3.06e-41: 140: 22.29
+	Hs
		673995 HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00		CLC2D_HUMAN (6-179): 2.47e-41: 139: 25.84
+	Hs
		674000 HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00		CLC4E_HUMAN (1-176): 8.25e-41: 138: 17.02
+	Hs
		488269 HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66		CLC4G_HUMAN (2-177): 1.85e-38: 134: 21.62
+	Hs
		354602 HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66		CLC4E_HUMAN (1-176): 8.25e-41: 138: 17.02
+	Hs
		673960 HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00		CL12B_HUMAN (53-176): 6.44e-39: 135: 32.06
+	Hs
		354302 HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66		NKG2A_HUMAN (10-178): 1.25e-36: 128: 31.95
+	Hs
		382491 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		CLC2B_HUMAN (50-178): 1.36e-34: 120: 26.72
+	Hs
		570305 HLAG_HUMAN (2-116): 6.98e-44: 147: 22.41		NKG2A_HUMAN (10-178): 1.25e-36: 128: 31.95
+	Hs
		488322 HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66		CLC2B_HUMAN (50-178): 1.36e-34: 120: 26.72
+	Hs
		673971 HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00		CLC2B_HUMAN (50-178): 1.36e-34: 120: 26.72
+	Hs
		570381 HLAG_HUMAN (2-116): 6.98e-44: 147: 22.41		MRC2_HUMAN (73-174): 1.04e-14: 73.1: 19.63