HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: SENP7 (Q9BQF6)
Sentrin-specific protease 7 (EC 3.4.22.-) (SUMO-1-specific protease 2) (Sentrin/SUMO-specific protease SENP7)
Gene: SENP7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	1.00	0.527

Property	Details
Experiments	24018422
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Peptidase_C48~Rad60-SLD
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 95 Hs			1 1050
+	Xl
		80969 SMO2B_XENLA (1-95): 1.18e-43: 138: 96.84		B7TYL2_XENLA (206-1048): 0: 671: 39.04
+	Sp
		140818 PMT3_SCHPO (7-93): 4.62e-37: 122: 50.58		ULP2_SCHPO (452-1048): 1.34e-121: 388: 21.80
+	Sp
		140841 PMT3_SCHPO (7-93): 4.62e-37: 122: 50.58		ULP1_SCHPO (456-960): 3.91e-99: 326: 14.80
+	Xl
		1151579 SMO2B_XENLA (1-95): 1.18e-43: 138: 96.84		Q804S7_XENLA (610-965): 2.35e-89: 301: 15.36
+	Hs
		902778 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SENP1_HUMAN (621-965): 7.85e-89: 300: 14.68
+	Hs
		902760 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SENP2_HUMAN (599-965): 7.51e-89: 299: 13.44
+	Hs
		879158 SUMO3_HUMAN (1-94): 3.76e-41: 132: 96.81		SENP1_HUMAN (621-965): 7.85e-89: 300: 14.68
+	Hs
		879156 SUMO3_HUMAN (1-94): 3.76e-41: 132: 96.81		SENP2_HUMAN (599-965): 7.51e-89: 299: 13.44
+	Hs
		928213 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		SENP1_HUMAN (621-965): 7.85e-89: 300: 14.68
+	Hs
		928203 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		SENP2_HUMAN (599-965): 7.51e-89: 299: 13.44
+	Hs
		902753 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SENP3_HUMAN (629-965): 5.55e-74: 257: 12.47
+	Xl
		1140103 SMO2B_XENLA (1-95): 1.18e-43: 138: 96.84		Q5XG28_XENLA (643-967): 3.73e-75: 257: 13.62
+	Hs
		902714 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SENP5_HUMAN (591-965): 1.31e-55: 209: 11.72
+	Xl
		78631 SMO2B_XENLA (1-95): 1.18e-43: 138: 96.84		B6RQN8_XENLA (360-965): 2.65e-55: 207: 12.91
+	Hs
		879147 SUMO3_HUMAN (1-94): 3.76e-41: 132: 96.81		SENP5_HUMAN (591-965): 1.31e-55: 209: 11.72
+	Dm
		332584 O97102_DROME (1-94): 1.24e-37: 123: 68.09		Q9VWK5_DROME (707-965): 1.7e-55: 212: 17.80
+	Xl
		80968 SMO2B_XENLA (1-95): 1.18e-43: 138: 96.84		B7TYL1_XENLA (899-1046): 1.75e-37: 155: 48.65
+	Mm
		1160381 SUMO3_MOUSE (1-94): 5.48e-43: 137: 95.75		SENP6_MOUSE (911-1047): 8.95e-38: 155: 54.75
+	Hs
		902747 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SENP6_HUMAN (911-1046): 1.23e-35: 149: 53.68
+	Hs
		928190 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		SENP6_HUMAN (911-1046): 1.23e-35: 149: 53.68