HitPredict

Interactor 1: UFM1 (P61960)
Ubiquitin-fold modifier 1
Gene: UFM1

Interactor 2: UBA5 (Q9GZZ9)
Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (ThiFP1) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)
Gene: UBA5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.975

The method score is based on:

Property Details
Experiments 26496610, 28514442, 24966333, 33961781, 35271311, 20562859, 15071506, 21304510, 26872069
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ThiF~Ufm1
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0033146 - regulation of intracellular estrogen receptor signaling pathway
GO:0034976 - response to endoplasmic reticulum stress
GO:0061709 - reticulophagy
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 85
Hs

1 404
+ Dm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024