HitPredict

Interactor 1: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: PCGF3 (Q3KNV8)
Polycomb group RING finger protein 3 (RING finger protein 3A)
Gene: PCGF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	27705803, 28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Hs			1 242
+	Hs
		718385 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF2_HUMAN (3-238): 5.76e-59: 191: 34.03
+	Hs
		903014 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF1_HUMAN (3-238): 1.66e-45: 154: 38.33
+	Hs
		903017 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF6_HUMAN (3-235): 4.63e-43: 150: 33.62
+	Hs
		902951 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF5_HUMAN (4-241): 3.95e-40: 140: 38.06
+	Hs
		903005 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		RING2_HUMAN (2-237): 3.42e-36: 132: 18.00
+	Mm
		903076 DCAF7_MOUSE (1-342): 5.45e-87: 267: 100.00		RING2_MOUSE (2-237): 2.47e-36: 132: 18.00
+	Hs
		902886 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		RING1_HUMAN (3-172): 3.16e-35: 131: 20.81
+	Mm
		1194979 Q80ZU1_MOUSE (1-342): 2.67e-85: 262: 99.71		RING2_MOUSE (2-237): 2.47e-36: 132: 18.00
+	Hs
		718223 SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38		BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76
+	Mm
		1141971 RBBP7_MOUSE (10-342): 1.03e-68: 222: 14.51		RING2_MOUSE (2-237): 2.47e-36: 132: 18.00
+	Mm
		1141950 RBBP4_MOUSE (10-342): 2.39e-68: 221: 13.98		RING2_MOUSE (2-237): 2.47e-36: 132: 18.00
+	Hs
		997870 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		RING2_HUMAN (2-237): 3.42e-36: 132: 18.00
+	Dm
		1279331 EBI_DROME (104-342): 5.77e-41: 153: 15.98		Q9VV77_DROME (2-241): 5.3e-50: 164: 54.55
+	Hs
		717626 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76
+	Hs
		903492 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		PCGF6_HUMAN (3-235): 4.63e-43: 150: 33.62
+	Hs
		903455 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		RING2_HUMAN (2-237): 3.42e-36: 132: 18.00
+	Mm
		903677 WDR5_MOUSE (208-342): 8.98e-29: 115: 11.85		RING2_MOUSE (2-237): 2.47e-36: 132: 18.00
+	Hs
		903159 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		RING1_HUMAN (3-172): 3.16e-35: 131: 20.81
+	Hs
		903378 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		COP1_HUMAN (17-94): 2.22e-10: 62.2: 25.64
+	Hs
		1246161 GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61		COP1_HUMAN (17-94): 2.22e-10: 62.2: 25.64