HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: ENL (Q03111)
Protein ENL (YEATS domain-containing protein 1)
Gene: MLLT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.585

Property	Details
Experiments	18829459, 18829457
Identification Methods	x-ray crystallography, pull down
Interaction Type	association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 559
+	Hs
		903600 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		YETS2_HUMAN (3-502): 1.64e-35: 144: 12.96
+	Hs
		903172 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		903405 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		CBP_HUMAN (36-507): 4.66e-27: 118: 11.67
+	Dm
		1358854 WDS_DROME (3-290): 7.53e-92: 279: 31.21		Q9VLL1_DROME (8-351): 2.33e-29: 125: 14.72
+	Hs
		209428 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		998787 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		1346967 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		YETS2_HUMAN (3-502): 1.64e-35: 144: 12.96
+	Hs
		317479 POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73		YETS4_HUMAN (6-138): 1.04e-41: 151: 25.18
+	Hs
		1288382 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		YETS2_HUMAN (3-502): 1.64e-35: 144: 12.96