HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: WDR59 (Q6PJI9)
GATOR2 complex protein WDR59 (WD repeat-containing protein 59)
Gene: WDR59

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	17041588
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 974
+	Hs
		1162302 TBL1R_HUMAN (82-333): 6.52e-60: 201: 26.28		WDR59_HUMAN (1-974): 0: 805: 100.00
+	Hs
		903077 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38
+	Hs
		903349 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5B_HUMAN (180-476): 5.68e-43: 161: 13.40
+	Hs
		196984 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PRP4_HUMAN (2-175): 7.43e-33: 136: 12.85
+	Hs
		903418 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		FBXW7_HUMAN (219-506): 1.23e-21: 102: 12.93
+	Hs
		903471 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		GRWD1_HUMAN (96-354): 6.12e-21: 99.1: 16.60
+	Hs
		903551 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		NLE1_HUMAN (3-88): 1.27e-17: 89.1: 7.78
+	Hs
		903171 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		RBBP4_HUMAN (145-377): 1.33e-17: 88.4: 20.39
+	Hs
		903428 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SNR40_HUMAN (268-503): 1.87e-17: 87.2: 9.09
+	Hs
		792949 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		LIS1_HUMAN (278-527): 1.09e-16: 85.6: 8.00
+	Dm
		1358845 WDS_DROME (3-290): 7.53e-92: 279: 31.21		WDS_DROME (2-179): 1.14e-42: 161: 13.44
+	Hs
		209416 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38
+	Hs
		792935 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		LIS1_HUMAN (278-527): 1.09e-16: 85.6: 8.00
+	Mm
		925836 LIS1_MOUSE (2-289): 1.02e-94: 288: 29.49		LIS1_MOUSE (278-527): 1.05e-16: 85.6: 8.00
+	Hs
		1240442 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		POC1A_HUMAN (268-629): 1.17e-19: 94.5: 9.52
+	Hs
		209467 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		SNR40_HUMAN (268-503): 1.87e-17: 87.2: 9.09
+	Ce
		954090 LIS1_CAEEL (2-289): 8.81e-87: 268: 24.68		LIN53_CAEEL (104-371): 8.15e-17: 86.1: 19.07
+	Hs
		1288273 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		SNR40_HUMAN (268-503): 1.87e-17: 87.2: 9.09