HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: DDX18 (Q9NVP1)
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)
Gene: DDX18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 670
+	Hs
		903410 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		571382 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Hs
		133956 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59
+	Hs
		903507 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		DDX47_HUMAN (192-524): 3.3e-64: 221: 39.82
+	Hs
		903437 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		DDX27_HUMAN (121-574): 3.56e-56: 206: 34.88
+	Hs
		1288337 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		DDX18_HUMAN (1-670): 5.81e-174: 513: 100.00
+	Sc
		630886 NLE1_YEAST (167-333): 3.95e-41: 152: 23.70		HAS1_YEAST (142-641): 8.13e-140: 420: 57.69
+	Hs
		1271679 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		1271615 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		134154 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59
+	Hs
		1271621 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		571547 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Hs
		181721 POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73		DDX3Y_HUMAN (24-577): 1.9e-128: 396: 23.27
+	Hs
		1333547 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		DDX31_HUMAN (87-619): 1.02e-81: 278: 33.71
+	Sc
		630846 NLE1_YEAST (167-333): 3.95e-41: 152: 23.70		SPB4_YEAST (197-618): 1.28e-57: 207: 32.29
+	Sc
		630853 NLE1_YEAST (167-333): 3.95e-41: 152: 23.70		DRS1_YEAST (191-523): 3.57e-56: 205: 38.30
+	Hs
		1288310 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		DDX31_HUMAN (87-619): 1.02e-81: 278: 33.71
+	Hs
		1292666 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		DDX27_HUMAN (121-574): 3.56e-56: 206: 34.88
+	Hs
		1288233 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		DDX27_HUMAN (121-574): 3.56e-56: 206: 34.88