Protein: MYO3
Myosin-3 (Actin-dependent myosin-I MYO3) (Class I unconventional myosin MYO3) (Type I myosin MYO3)

Gene: MYO3
Organism: Saccharomyces cerevisiae S288C
Interactions: 112
UniProt ID: P36006

Gene Ontology (top 5):
GO:0000146 - microfilament motor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006887 - exocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449111

CALM
Calmodulin

4

20

Small-scale

0.890

High

778997

BBC1
Myosin tail region-interacting protein MTI1

3

12

Small-scale

0.888

High

779019

MYO5
Myosin-5

3

20

High-throughput

0.868

High

778999

CLA4
Serine/threonine-protein kinase CLA4

2

17

Small-scale

0.778

High

778974

VRP1
Verprolin

7

10

Small-scale

0.751

High

779029

LAS17
Proline-rich protein LAS17

6

7

Small-scale

0.738

High

779030

OSH2
Oxysterol-binding protein homolog 2

1

4

High-throughput

0.733

High

744987

YSC84
Protein YSC84

1

11

High-throughput

0.698

High

779012

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

3

16

High-throughput

0.680

High

778993

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

3

15

Small-scale

0.668

High

736083

ARP2
Actin-related protein 2

1

20

Small-scale

0.665

High

779005

YGZ2
Ankyrin repeat-containing protein YGL242C

1

15

High-throughput

0.665

High

778992

BNR1
BNI1-related protein 1

3

8

Small-scale

0.660

High

779004

SHE4
SWI5-dependent HO expression protein 4

3

2

Small-scale

0.658

High

778982

BZZ1
Protein BZZ1

1

3

High-throughput

0.656

High

778986

RV167
Reduced viability upon starvation protein 167

1

14

High-throughput

0.656

High

778978

ARPC1
Actin-related protein 2/3 complex subunit 1

2

20

Small-scale

0.639

High

750329

ARPC4
Actin-related protein 2/3 complex subunit 4

2

4

Small-scale

0.631

High

523579

HSP71
Heat shock protein SSA1

3

10

High-throughput

0.624

High

544430

SSB1
Ribosome-associated molecular chaperone SSB1

3

10

High-throughput

0.624

High

779024

SRL1
Cell wall protein SRL1

2

1

High-throughput

0.620

High

744824

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

6

High-throughput

0.618

High

778970

MYO3
Myosin-3

1

19

High-throughput

0.618

High

778983

END3
Actin cytoskeleton-regulatory complex protein END3

2

3

High-throughput

0.614

High

779017

STE20
Serine/threonine-protein kinase STE20

2

20

Small-scale

0.602

High

739061

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

8

Small-scale

0.573

High

778996

BNI1
Protein BNI1

1

8

High-throughput

0.573

High

778988

SAP1
Protein SAP1

1

6

High-throughput

0.568

High

364467

CDK1
Cyclin-dependent kinase 1

1

12

High-throughput

0.561

High

779011

2ABA
Protein phosphatase PP2A regulatory subunit B

1

1

High-throughput

0.541

High

779014

STD1
Protein STD1

1

3

High-throughput

0.541

High

779015

MET31
Transcriptional regulator MET31

1

1

High-throughput

0.541

High

751632

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.518

High

359197

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.508

High

751723

PRP8
Pre-mRNA-splicing factor 8

1

2

High-throughput

0.501

High

778989

ZRG8
Zinc-regulated protein 8

1

1

High-throughput

0.501

High

778995

AIM21
Altered inheritance of mitochondria protein 21

1

5

High-throughput

0.501

High

779006

MDS3
Negative regulator of sporulation MDS3

1

1

High-throughput

0.501

High

779010

APP1
Phosphatidate phosphatase APP1

1

1

High-throughput

0.501

High

779018

VPS64
Vacuolar protein sorting-associated protein 64

1

2

High-throughput

0.501

High

763708

MTH1
Protein MTH1

1

3

High-throughput

0.494

High

778998

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

2

High-throughput

0.494

High

672871

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.493

High

779009

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.493

High

779016

GCN5
Histone acetyltransferase GCN5

1

10

High-throughput

0.489

High

779020

CYK2
Cytokinesis protein 2

1

6

Small-scale

0.481

High

150109

YH11B
Transposon Ty1-H Gag-Pol polyprotein

1

0

High-throughput

0.480

High

778971

RCN1
Calcipressin-like protein

1

0

High-throughput

0.480

High

778972

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

0

High-throughput

0.480

High

778976

SMP1
Transcription factor SMP1

1

0

High-throughput

0.480

High

149689

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

434992

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

514566

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

526379

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.479

High

674540

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

709689

BMH1
Protein BMH1

1

5

High-throughput

0.479

High

778253

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

778975

GBLP
Small ribosomal subunit protein RACK1

1

12

High-throughput

0.479

High

778979

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

778980

OSH3
Oxysterol-binding protein homolog 3

1

4

High-throughput

0.479

High

778984

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.479

High

778985

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

778994

ARPC5
Actin-related protein 2/3 complex subunit 5

1

5

High-throughput

0.479

High

779000

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

779008

ARPC2
Actin-related protein 2/3 complex subunit 2

1

5

High-throughput

0.479

High

779013

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

779021

ENT2
Epsin-2

1

3

High-throughput

0.479

High

779022

ARPC3
Actin-related protein 2/3 complex subunit 3

1

6

High-throughput

0.479

High

779023

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

779031

ENT1
Epsin-1

1

3

High-throughput

0.479

High

368643

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.464

High

668481

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.464

High

778973

SUMT
Uroporphyrinogen-III C-methyltransferase

1

1

High-throughput

0.464

High

645364

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

778977

IST2
Increased sodium tolerance protein 2

1

0

High-throughput

0.458

High

779007

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

779026

YO389
Uncharacterized protein YOR389W

1

3

High-throughput

0.457

High

779027

YP277
Uncharacterized protein YPL277C

1

3

High-throughput

0.457

High

394438

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

486125

TBA1
Tubulin alpha-1 chain

1

7

High-throughput

0.445

High

579180

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.445

High

675897

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

741328

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.445

High

742819

HSP79
Heat shock protein homolog SSE2

1

16

High-throughput

0.445

High

752108

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

778990

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

778991

TCPE
T-complex protein 1 subunit epsilon

1

1

High-throughput

0.445

High

779003

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.445

High

383626

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

433564

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

441834

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

454983

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

502969

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

512366

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

512930

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.437

High

689374

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

706753

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

740712

SRP40
Suppressor protein SRP40

1

7

High-throughput

0.437

High

747285

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

753292

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

779025

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

569965

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.426

High

779002

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.426

High

779028

YDR10
Uncharacterized protein YDR010C

1

1

High-throughput

0.417

High

712537

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.407

High

734815

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.269

Low

778981

RRP4
Exosome complex component RRP4

1

0

High-throughput

0.269

Low

676526

PUT3
Proline utilization trans-activator

1

0

Small-scale

0.261

Low

778987

PTI1
Protein PTI1

1

0

High-throughput

0.261

Low

779001

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

585252

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025