Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: ASH2L (Q9UBL3)
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)
Gene: ASH2L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 26186194, 25666610, 28514442, 27705803, 32076268, 33022573, 33961781, 16878130, 16253997, 33472061, 15960974, 18066051, 21531708, 20305087, 21884981, 23870121, 15199122, 31076518, 31544921, 24981860 and 7 others

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Identification Methods affinity chromatography technology, biochemical, pull down, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0035097 - histone methyltransferase complex
GO:0044665 - MLL1/2 complex
GO:0044666 - MLL3/4 complex
and 3 others

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Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 334
Hs

1 628
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+ Sp
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024