HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	34857003, 35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Hs			1 768
+	Mm
		904359 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		CUL3_MOUSE (1-768): 0: 949: 99.48
+	Hs
		903928 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		903929 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		903925 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		903926 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1041629 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042207 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041628 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042958 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		904069 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		1043495 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1040994 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041129 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1040993 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041235 IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041328 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1041424 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1041327 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1273045 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		1071954 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		CUL5_HUMAN (25-768): 0: 597: 23.77