HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: CIRBP (Q14011)
Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)
Gene: CIRBP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.739

Property	Details
Experiments	29892012, 22365833, 25416956, 21516116, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0010494 - cytoplasmic stress granule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Hs			1 172
+	Mm
		892745 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		CIRBP_MOUSE (1-172): 1.09e-39: 134: 95.35
+	Mm
		292633 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		RBM3_MOUSE (1-166): 4.16e-34: 119: 57.23
+	Hs
		903887 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		516439 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Mm
		665747 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		PABP1_MOUSE (7-162): 4.81e-26: 105: 18.59
+	Hs
		745112 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		483434 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		RBY1A_HUMAN (2-118): 7.64e-16: 75.9: 51.28
+	Mm
		904226 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		TRA2B_MOUSE (8-132): 2.95e-15: 73.2: 46.40
+	Hs
		903951 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57
+	Mm
		904286 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		ROA3_MOUSE (7-90): 1.06e-09: 58.2: 35.71
+	Dm
		90914 M9NF14_DROME (115-458): 5.28e-26: 113: 17.77		E1JJ00_DROME (2-118): 1.58e-16: 77.6: 26.45
+	Hs
		958266 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		1031509 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		PABP4_HUMAN (7-170): 1.39e-28: 112: 20.12
+	Hs
		516531 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		516769 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Mm
		857294 PCBP1_MOUSE (23-127): 3.42e-12: 69.7: 23.15		TIA1_MOUSE (2-164): 5.99e-19: 84.1: 18.33
+	Hs
		745178 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		963557 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		TIAR_HUMAN (2-151): 1.75e-16: 77.2: 20.53
+	Hs
		963587 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		TIAR_HUMAN (2-151): 1.75e-16: 77.2: 20.53
+	Hs
		852215 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		ROA3_HUMAN (7-92): 2.98e-14: 70.9: 43.02