HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: CGNL1 (Q0VF96)
Cingulin-like protein 1 (Junction-associated coiled-coil protein) (Paracingulin)
Gene: CGNL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	33961781, 36931259, 20936779, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1302
+	Hs
		909488 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CGNL1_HUMAN (776-1302): 2.16e-28: 126: 13.45
+	Hs
		728460 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYH11_HUMAN (150-955): 1.88e-27: 123: 9.06
+	Hs
		981958 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CGNL1_HUMAN (776-1302): 2.16e-28: 126: 13.45
+	Hs
		728471 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MYH11_HUMAN (150-955): 1.88e-27: 123: 9.06
+	Hs
		927643 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		MYH2_HUMAN (292-1302): 2.76e-46: 185: 11.52
+	Hs
		725130 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYH10_HUMAN (172-796): 3.17e-20: 99: 8.79
+	Hs
		725128 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MYH10_HUMAN (172-796): 3.17e-20: 99: 8.79
+	Hs
		910117 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CING_HUMAN (351-748): 5.8e-09: 62.9: 10.86
+	Hs
		905210 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CING_HUMAN (351-748): 5.8e-09: 62.9: 10.86
+	Hs
		982579 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CING_HUMAN (351-748): 5.8e-09: 62.9: 10.86
+	Hs
		683298 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		CGNL1_HUMAN (776-1302): 2.16e-28: 126: 13.45
+	Hs
		926974 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		CGNL1_HUMAN (776-1302): 2.16e-28: 126: 13.45
+	Hs
		728466 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		MYH11_HUMAN (150-955): 1.88e-27: 123: 9.06
+	Hs
		522602 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		MYH7_HUMAN (795-1302): 3.01e-25: 116: 13.51
+	Mm
		926804 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		MYH10_MOUSE (135-796): 3.35e-19: 96.5: 8.11
+	Hs
		502907 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		MYH3_HUMAN (85-743): 1.05e-17: 91.8: 10.08
+	Hs
		724761 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		MYH9_HUMAN (883-1302): 6.99e-15: 82.6: 15.84
+	Mm
		926855 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		MYH9_MOUSE (917-1302): 3.95e-14: 79.9: 14.51
+	Hs
		683782 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		CING_HUMAN (351-748): 5.8e-09: 62.9: 10.86
+	Hs
		927614 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		CING_HUMAN (351-748): 5.8e-09: 62.9: 10.86