HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: GIT2 (Q14161)
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Gene: GIT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion GO:0098793 - presynapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 759
+	Mm
		910346 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		GIT2_MOUSE (1-759): 5.02e-146: 446: 83.00
+	Mm
		910271 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		GIT1_MOUSE (1-758): 1.06e-139: 431: 63.43
+	Hs
		910161 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AGAP1_HUMAN (3-224): 1.19e-59: 218: 33.33
+	Hs
		904575 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ACAP1_HUMAN (3-295): 4.06e-61: 221: 23.39
+	Hs
		909925 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AGAP3_HUMAN (3-224): 5.35e-57: 211: 35.11
+	Hs
		91532 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		E7EUN2_HUMAN (3-224): 2.01e-57: 214: 33.33
+	Hs
		905003 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AGAP3_HUMAN (3-224): 5.35e-57: 211: 35.11
+	Hs
		161349 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYPT1_HUMAN (94-670): 7.76e-54: 203: 10.75
+	Hs
		60315 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		POTEF_HUMAN (79-665): 1.93e-53: 202: 12.79
+	Hs
		161346 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MYPT1_HUMAN (94-670): 7.76e-54: 203: 10.75
+	Hs
		60314 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		POTEF_HUMAN (79-665): 1.93e-53: 202: 12.79
+	Hs
		909866 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ARAP2_HUMAN (7-186): 2.94e-51: 196: 32.24
+	Hs
		904928 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ARAP2_HUMAN (7-186): 2.94e-51: 196: 32.24
+	Hs
		909455 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ANK2_HUMAN (108-437): 3.9e-45: 177: 13.13
+	Hs
		257595 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ANR17_HUMAN (41-254): 6.34e-28: 123: 16.28
+	Hs
		909789 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ANKH1_HUMAN (41-254): 3.8e-27: 120: 16.28
+	Hs
		257593 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ANR17_HUMAN (41-254): 6.34e-28: 123: 16.28
+	Hs
		904829 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ANKH1_HUMAN (41-254): 3.8e-27: 120: 16.28
+	Hs
		910104 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RAI14_HUMAN (120-504): 2.87e-16: 85.4: 16.58
+	Hs
		909582 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ACAP2_HUMAN (72-237): 4.27e-13: 75.2: 22.89