HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: ACAP1 (Q15027)
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Centaurin-beta-1) (Cnt-b1)
Gene: ACAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 740
+	Hs
		909582 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ACAP2_HUMAN (1-738): 4.05e-150: 458: 48.09
+	Hs
		909925 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AGAP3_HUMAN (319-663): 3.47e-90: 303: 30.46
+	Hs
		905003 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AGAP3_HUMAN (319-663): 3.47e-90: 303: 30.46
+	Hs
		982396 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		AGAP3_HUMAN (319-663): 3.47e-90: 303: 30.46
+	Hs
		910141 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DP13A_HUMAN (4-399): 2.66e-76: 262: 18.05
+	Hs
		905240 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DP13A_HUMAN (4-399): 2.66e-76: 262: 18.05
+	Hs
		909830 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DP13B_HUMAN (4-409): 4.86e-73: 252: 16.19
+	Hs
		909999 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TANC1_HUMAN (15-729): 8.94e-69: 248: 13.99
+	Hs
		905087 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TANC1_HUMAN (15-729): 8.94e-69: 248: 13.99
+	Hs
		909789 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ANKH1_HUMAN (334-706): 3.04e-31: 133: 13.30
+	Hs
		904829 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ANKH1_HUMAN (334-706): 3.04e-31: 133: 13.30
+	Hs
		91532 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		E7EUN2_HUMAN (228-699): 3.36e-25: 114: 14.32
+	Hs
		910161 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AGAP1_HUMAN (228-699): 5.33e-23: 106: 14.56
+	Hs
		905263 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AGAP1_HUMAN (228-699): 5.33e-23: 106: 14.56
+	Hs
		91533 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		E7EUN2_HUMAN (228-699): 3.36e-25: 114: 14.32
+	Hs
		904910 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SMAP2_HUMAN (407-545): 3.21e-21: 99: 38.73
+	Hs
		982321 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		SMAP2_HUMAN (407-545): 3.21e-21: 99: 38.73
+	Hs
		909717 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		FGD6_HUMAN (183-357): 9.98e-10: 64.2: 18.68
+	Hs
		904753 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		FGD6_HUMAN (183-357): 9.98e-10: 64.2: 18.68
+	Hs
		982180 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		FGD6_HUMAN (183-357): 9.98e-10: 64.2: 18.68