HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: K2C1B (Q7Z794)
Keratin, type II cytoskeletal 1b (Cytokeratin-1B) (CK-1B) (Keratin-77) (K77) (Type-II keratin Kb39)
Gene: KRT77

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 578
+	Hs
		409044 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		409042 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		380563 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		K2C1_HUMAN (129-510): 2.95e-163: 481: 68.06
+	Hs
		409055 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		380568 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		K2C1_HUMAN (129-510): 2.95e-163: 481: 68.06
+	Hs
		982264 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		K2C78_HUMAN (88-523): 1e-117: 360: 50.89
+	Hs
		409014 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		409047 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		409008 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		409015 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		904437 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KRT85_HUMAN (39-485): 6.33e-88: 282: 43.11
+	Hs
		927293 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		K2C78_HUMAN (88-523): 1e-117: 360: 50.89
+	Hs
		905163 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KRT82_HUMAN (47-559): 8.9e-84: 272: 40.16
+	Hs
		909746 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		K2C1B_HUMAN (1-578): 3.81e-74: 249: 100.00
+	Mm
		910243 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		K22O_MOUSE (1-504): 3.95e-74: 249: 54.51
+	Hs
		982214 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		K2C1B_HUMAN (1-578): 3.81e-74: 249: 100.00
+	Hs
		904944 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KRT35_HUMAN (48-477): 1.17e-64: 220: 23.20
+	Hs
		380460 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		K2C6B_HUMAN (3-496): 3.98e-82: 269: 58.38
+	Hs
		683500 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		K2C1B_HUMAN (1-578): 3.81e-74: 249: 100.00
+	Hs
		927229 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		K2C1B_HUMAN (1-578): 3.81e-74: 249: 100.00