Protein: PDS5B
Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3)

Gene: PDS5B
Organism: Homo sapiens
Interactions: 171
UniProt ID: Q9NTI5

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1177650

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

5

7

Small-scale

0.912

High

238622

RAD21
Double-strand-break repair protein rad21 homolog

11

11

Small-scale

0.757

High

1449518

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

2

11

Small-scale

0.754

High

1130199

SMC1A
Structural maintenance of chromosomes protein 1A

8

20

Small-scale

0.750

High

1449532

SMC3
Structural maintenance of chromosomes protein 3

6

20

Small-scale

0.736

High

1279239

WAPL
Wings apart-like protein homolog

5

3

Small-scale

0.718

High

1390542

CDCA5
Sororin

5

2

Small-scale

0.716

High

1325398

STAG2
Cohesin subunit SA-2

5

18

Small-scale

0.709

High

1358307

STAG1
Cohesin subunit SA-1

5

18

Small-scale

0.709

High

166425

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

5

3

High-throughput

0.648

High

1315279

SEP12
Septin-12

3

0

High-throughput

0.638

High

373264

MYC
Myc proto-oncogene protein

3

16

High-throughput

0.633

High

262320

SCN2B
Sodium channel regulatory subunit beta-2

4

5

High-throughput

0.630

High

774658

BASI
Basigin

4

4

High-throughput

0.630

High

592955

ANK1
Ankyrin-1

2

6

High-throughput

0.628

High

1449520

SCN3B
Sodium channel regulatory subunit beta-3

2

6

High-throughput

0.628

High

904389

BRCA2
Breast cancer type 2 susceptibility protein

2

0

Small-scale

0.620

High

332713

LYPD3
Ly6/PLAUR domain-containing protein 3

3

1

High-throughput

0.609

High

1055980

RAD51
DNA repair protein RAD51 homolog 1

2

0

Small-scale

0.592

High

1294961

PALB2
Partner and localizer of BRCA2

2

0

Small-scale

0.592

High

755004

H2B1B
Histone H2B type 1-B

2

20

High-throughput

0.584

High

998858

H31
Histone H3.1

2

20

High-throughput

0.584

High

1372318

H2B1H
Histone H2B type 1-H

2

20

High-throughput

0.584

High

1449523

PD1L1
Programmed cell death 1 ligand 1

2

5

High-throughput

0.584

High

60749

F234B
Protein FAM234B

2

2

High-throughput

0.574

High

406930

MAS
Proto-oncogene Mas

2

17

High-throughput

0.574

High

438106

GLPB
Glycophorin-B

2

3

High-throughput

0.574

High

466979

ACM4
Muscarinic acetylcholine receptor M4

2

2

High-throughput

0.574

High

702855

5HT2C
5-hydroxytryptamine receptor 2C

2

2

High-throughput

0.574

High

749282

CD70
CD70 antigen

2

2

High-throughput

0.574

High

771243

APJ
Apelin receptor

2

10

High-throughput

0.574

High

835403

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

2

High-throughput

0.574

High

854589

S15A1
Solute carrier family 15 member 1

2

3

High-throughput

0.574

High

1406350

LPAR4
Lysophosphatidic acid receptor 4

2

12

High-throughput

0.574

High

1353793

HASP
Serine/threonine-protein kinase haspin

1

3

Small-scale

0.552

High

182793

GP182
G-protein coupled receptor 182

2

16

High-throughput

0.549

High

754110

CD80
T-lymphocyte activation antigen CD80

2

5

High-throughput

0.549

High

210426

MTLR
Motilin receptor

1

7

High-throughput

0.536

High

388310

GLPA
Glycophorin-A

1

3

High-throughput

0.536

High

549698

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

3

High-throughput

0.536

High

551286

PCNA
Proliferating cell nuclear antigen

1

2

Small-scale

0.536

High

611989

RL35A
Large ribosomal subunit protein eL33

1

1

High-throughput

0.536

High

1449533

KLH20
Kelch-like protein 20

1

5

High-throughput

0.536

High

1037399

H11
Histone H1.1

1

11

High-throughput

0.515

High

1449528

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

4

High-throughput

0.515

High

281253

CDC45
Cell division control protein 45 homolog

1

0

Small-scale

0.513

High

423286

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

1204399

SGO1
Shugoshin 1

1

2

Small-scale

0.500

High

71254

HIDE1
Protein HIDE1

1

1

High-throughput

0.489

High

209118

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.489

High

328747

VAMP5
Vesicle-associated membrane protein 5

1

1

High-throughput

0.489

High

832450

OPRX
Nociceptin receptor

1

6

High-throughput

0.489

High

914353

EFNA4
Ephrin-A4

1

1

High-throughput

0.489

High

957025

CXCR4
C-X-C chemokine receptor type 4

1

11

High-throughput

0.489

High

1101676

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

12

High-throughput

0.489

High

1281715

B3GN8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

1

1

High-throughput

0.489

High

1399626

OPALI
Opalin

1

2

High-throughput

0.489

High

1407305

CML1
Chemerin-like receptor 1

1

13

High-throughput

0.489

High

1430693

F234A
Protein FAM234A

1

2

High-throughput

0.489

High

1449524

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

1

High-throughput

0.489

High

1449525

HCST
Hematopoietic cell signal transducer

1

1

High-throughput

0.489

High

1449529

CC018
Uncharacterized protein C3orf18

1

1

High-throughput

0.489

High

1449535

NPTN
Neuroplastin

1

6

High-throughput

0.489

High

564432

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.481

High

129468

MEN1
Menin

1

6

High-throughput

0.479

High

157906

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.479

High

170377

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

191119

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

9

High-throughput

0.479

High

218829

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

223365

PRC1
Protein regulator of cytokinesis 1

1

5

High-throughput

0.479

High

257001

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.479

High

260513

BRD4
Bromodomain-containing protein 4

1

12

High-throughput

0.479

High

272489

OBSL1
Obscurin-like protein 1

1

12

High-throughput

0.479

High

285490

EED
Polycomb protein EED

1

18

High-throughput

0.479

High

331355

KI20A
Kinesin-like protein KIF20A

1

12

High-throughput

0.479

High

406698

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.479

High

412676

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.479

High

419231

H2A1B
Histone H2A type 1-B/E

1

7

High-throughput

0.479

High

449797

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.479

High

456865

ANXA2
Annexin A2

1

2

High-throughput

0.479

High

487798

PARP1
Poly [ADP-ribose] polymerase 1

1

12

High-throughput

0.479

High

537974

HSP7C
Heat shock cognate 71 kDa protein

1

9

High-throughput

0.479

High

542671

TOP2A
DNA topoisomerase 2-alpha

1

4

High-throughput

0.479

High

581319

RAC2
Ras-related C3 botulinum toxin substrate 2

1

11

High-throughput

0.479

High

589809

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

659951

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.479

High

696627

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

697269

APEX1
DNA repair nuclease/redox regulator APEX1

1

4

High-throughput

0.479

High

729622

CASPE
Caspase-14

1

2

High-throughput

0.479

High

769295

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

800124

COIL
Coilin

1

2

High-throughput

0.479

High

831502

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

840127

CASP2
Caspase-2

1

2

High-throughput

0.479

High

879510

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

883708

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

905184

MECP2
Methyl-CpG-binding protein 2

1

8

High-throughput

0.479

High

910218

RND2
Rho-related GTP-binding protein RhoN

1

18

High-throughput

0.479

High

943424

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.479

High

946893

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.479

High

955655

CDC42
Cell division control protein 42 homolog

1

13

High-throughput

0.479

High

965268

WDR5
WD repeat-containing protein 5

1

8

High-throughput

0.479

High

978341

RHOB
Rho-related GTP-binding protein RhoB

1

14

High-throughput

0.479

High

979284

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

980409

H4
Histone H4

1

8

High-throughput

0.479

High

981129

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

985020

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

996870

TBA1B
Tubulin alpha-1B chain

1

8

High-throughput

0.479

High

1005140

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.479

High

1017243

H33
Histone H3.3

1

20

High-throughput

0.479

High

1023184

RBM10
RNA-binding protein 10

1

7

High-throughput

0.479

High

1045821

TF65
Transcription factor p65

1

7

High-throughput

0.479

High

1097589

CBX3
Chromobox protein homolog 3

1

16

High-throughput

0.479

High

1100436

TIF1B
Transcription intermediary factor 1-beta

1

8

High-throughput

0.479

High

1107254

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1140924

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

1141330

BRD3
Bromodomain-containing protein 3

1

13

High-throughput

0.479

High

1141965

EEA1
Early endosome antigen 1

1

15

High-throughput

0.479

High

1144320

STK38
Serine/threonine-protein kinase 38

1

5

High-throughput

0.479

High

1155817

EZH2
Histone-lysine N-methyltransferase EZH2

1

15

High-throughput

0.479

High

1160842

NFIL3
Nuclear factor interleukin-3-regulated protein

1

9

High-throughput

0.479

High

1163239

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.479

High

1208900

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.479

High

1241811

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

High-throughput

0.479

High

1276847

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.479

High

1313463

SMC5
Structural maintenance of chromosomes protein 5

1

20

High-throughput

0.479

High

1314440

SLX4
Structure-specific endonuclease subunit SLX4

1

14

High-throughput

0.479

High

1338991

NUP43
Nucleoporin Nup43

1

18

High-throughput

0.479

High

1359934

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

2

High-throughput

0.479

High

1404788

RING2
E3 ubiquitin-protein ligase RING2

1

7

High-throughput

0.479

High

1407907

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

1407999

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.479

High

1408058

H2B1L
Histone H2B type 1-L

1

20

High-throughput

0.479

High

1414054

SPNDC
Spindlin interactor and repressor of chromatin-binding protein

1

1

High-throughput

0.479

High

1414586

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.479

High

1417491

FACD2
Fanconi anemia group D2 protein

1

6

High-throughput

0.479

High

1438180

RHOF
Rho-related GTP-binding protein RhoF

1

17

High-throughput

0.479

High

1448199

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

6

High-throughput

0.479

High

1449521

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

7

High-throughput

0.479

High

1449522

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1449527

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1449531

CE164
Centrosomal protein of 164 kDa

1

16

High-throughput

0.479

High

1449534

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

1397230

PPR36
Protein phosphatase 1 regulatory subunit 36

1

1

High-throughput

0.470

High

248106

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

1101050

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

1167043

ZSWM7
Zinc finger SWIM domain-containing protein 7

1

0

Small-scale

0.458

High

1211619

TEX35
Testis-expressed protein 35

1

0

High-throughput

0.458

High

1238953

SWAP1
ATPase SWSAP1

1

0

Small-scale

0.458

High

1338391

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1383257

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

330337

VENTX
Homeobox protein VENTX

1

3

High-throughput

0.445

High

1395032

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

946264

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

1

High-throughput

0.437

High

1034358

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

8

High-throughput

0.437

High

1213847

KPRP
Keratinocyte proline-rich protein

1

1

High-throughput

0.437

High

1249251

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

1255735

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

1350226

WFDC5
WAP four-disulfide core domain protein 5

1

1

Small-scale

0.437

High

1393736

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

1396640

RHOV
Rho-related GTP-binding protein RhoV

1

13

High-throughput

0.437

High

1434006

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.437

High

1449519

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

7

High-throughput

0.437

High

1449530

HECD1
E3 ubiquitin-protein ligase HECTD1

1

9

High-throughput

0.437

High

887256

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.408

High

638531

FPR1
fMet-Leu-Phe receptor

1

13

High-throughput

0.407

High

886142

CXCR3
C-X-C chemokine receptor type 3

1

8

High-throughput

0.407

High

1372445

P2RX5
P2X purinoceptor 5

2

0

High-throughput

0.328

High

1022482

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1064266

CP4F3
Cytochrome P450 4F3

1

0

High-throughput

0.269

Low

1449526

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025