HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: MINK1 (Q8N4C8)
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)
Gene: MINK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1332
+	Hs
		909810 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MINK1_HUMAN (1-1332): 0: 1277: 100.00
+	Hs
		324772 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324769 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		909730 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MARK2_HUMAN (8-747): 3.42e-132: 427: 14.86
+	Mm
		910234 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		MARK2_MOUSE (8-747): 1.31e-130: 423: 14.66
+	Hs
		904766 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MARK2_HUMAN (8-747): 3.42e-132: 427: 14.86
+	Xl
		223345 O57468_XENLA (1-244): 4.25e-141: 397: 63.12		Q8QGV3_XENLA (2-747): 6.26e-129: 418: 13.86
+	Mm
		905332 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		MARK2_MOUSE (8-747): 1.31e-130: 423: 14.66
+	At
		1280891 14337_ARATH (3-244): 3.18e-142: 400: 60.25		CIPKC_ARATH (9-464): 5.99e-128: 405: 21.21
+	At
		788672 14333_ARATH (1-244): 4.4e-142: 400: 61.79		CIPKC_ARATH (9-464): 5.99e-128: 405: 21.21
+	Mm
		910231 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		MARK3_MOUSE (16-747): 5.13e-125: 407: 14.31
+	At
		965360 14332_ARATH (4-244): 1.39e-141: 398: 61.32		CIPKC_ARATH (9-464): 5.99e-128: 405: 21.21
+	Mm
		905331 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		MARK3_MOUSE (16-747): 5.13e-125: 407: 14.31
+	Hs
		909916 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MARK4_HUMAN (16-739): 9.59e-118: 387: 17.15
+	Hs
		909512 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		STK3_HUMAN (3-507): 3.96e-120: 384: 30.12
+	Hs
		909462 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		M3K10_HUMAN (21-845): 1.48e-113: 381: 19.26
+	Hs
		909502 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		STK4_HUMAN (5-469): 5.1e-119: 381: 32.99
+	Hs
		904517 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		STK3_HUMAN (3-507): 3.96e-120: 384: 30.12
+	Hs
		904461 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		M3K10_HUMAN (21-845): 1.48e-113: 381: 19.26
+	Hs
		904507 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		STK4_HUMAN (5-469): 5.1e-119: 381: 32.99