HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31300519
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 581
+	Hs
		909982 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		783970 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KPCI_HUMAN (56-568): 6.26e-123: 376: 13.92
+	Hs
		783968 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KPCI_HUMAN (56-568): 6.26e-123: 376: 13.92
+	Hs
		681770 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	At
		965291 14332_ARATH (4-244): 1.39e-141: 398: 61.32		CDPK1_ARATH (109-560): 2.31e-116: 360: 16.60
+	At
		802001 14334_ARATH (4-244): 5e-140: 395: 60.91		CDPK1_ARATH (109-560): 2.31e-116: 360: 16.60
+	Hs
		681766 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		904473 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		568616 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	At
		1280891 14337_ARATH (3-244): 3.18e-142: 400: 60.25		CIPKC_ARATH (183-553): 8.16e-102: 318: 15.63
+	At
		788672 14333_ARATH (1-244): 4.4e-142: 400: 61.79		CIPKC_ARATH (183-553): 8.16e-102: 318: 15.63
+	At
		965360 14332_ARATH (4-244): 1.39e-141: 398: 61.32		CIPKC_ARATH (183-553): 8.16e-102: 318: 15.63
+	Hs
		909590 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KS6A2_HUMAN (197-576): 4.99e-92: 300: 15.42
+	Hs
		850630 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KS6A3_HUMAN (154-555): 2.08e-92: 301: 16.59
+	Hs
		904590 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KS6A1_HUMAN (157-555): 9.95e-91: 296: 15.63
+	Hs
		910174 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KCC2A_HUMAN (221-538): 5.11e-82: 266: 20.62
+	Hs
		909532 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KCC2D_HUMAN (267-505): 9.96e-51: 184: 26.14
+	Hs
		909531 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KCC2G_HUMAN (225-505): 1.35e-49: 182: 22.92
+	Hs
		904532 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KCC2D_HUMAN (267-505): 9.96e-51: 184: 26.14
+	Hs
		904531 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KCC2G_HUMAN (225-505): 1.35e-49: 182: 22.92