HitPredict

Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: RASF7 (Q02833)
Ras association domain-containing protein 7 (HRAS1-related cluster protein 1)
Gene: RASSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	24366813, 26186194, 28514442, 28330616, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 373
+	Hs
		737754 PP1G_HUMAN (1-330): 0: 579: 90.66		RASF7_HUMAN (1-373): 7.27e-135: 391: 100.00
+	Hs
		906419 PP1B_HUMAN (1-330): 0: 568: 87.88		RASF7_HUMAN (1-373): 7.27e-135: 391: 100.00
+	Hs
		277406 PP1A_HUMAN (1-330): 0: 614: 100.00		RASF9_HUMAN (9-317): 2.1e-112: 336: 17.69
+	Hs
		277404 PP1G_HUMAN (1-330): 0: 579: 90.66		RASF9_HUMAN (9-317): 2.1e-112: 336: 17.69
+	Hs
		277407 PP1B_HUMAN (1-330): 0: 568: 87.88		RASF9_HUMAN (9-317): 2.1e-112: 336: 17.69
+	Mm
		906278 PP1A_MOUSE (1-330): 0: 614: 99.70		ASPP1_MOUSE (5-340): 9.36e-89: 290: 16.88
+	Hs
		906081 PP1A_HUMAN (1-330): 0: 614: 100.00		ASPP1_HUMAN (5-340): 7.7e-84: 277: 15.33
+	Hs
		906026 PP1A_HUMAN (1-330): 0: 614: 100.00		RASF8_HUMAN (8-308): 3.84e-85: 266: 35.41
+	Hs
		63639 PP1A_HUMAN (1-330): 0: 614: 100.00		RASFA_HUMAN (9-313): 8.7e-79: 252: 15.10
+	Hs
		737981 PP1G_HUMAN (1-330): 0: 579: 90.66		ASPP1_HUMAN (5-340): 7.7e-84: 277: 15.33
+	Hs
		737935 PP1G_HUMAN (1-330): 0: 579: 90.66		RASF8_HUMAN (8-308): 3.84e-85: 266: 35.41
+	Hs
		906562 PP1B_HUMAN (1-330): 0: 568: 87.88		ASPP1_HUMAN (5-340): 7.7e-84: 277: 15.33
+	Hs
		906539 PP1B_HUMAN (1-330): 0: 568: 87.88		RASF8_HUMAN (8-308): 3.84e-85: 266: 35.41
+	Mm
		93784 PP1A_MOUSE (1-330): 0: 614: 99.70		E9QJU8_MOUSE (5-365): 2.56e-39: 151: 15.31
+	Hs
		905884 PP1A_HUMAN (1-330): 0: 614: 100.00		ASPP2_HUMAN (5-353): 5.06e-39: 150: 14.21
+	Hs
		737795 PP1G_HUMAN (1-330): 0: 579: 90.66		ASPP2_HUMAN (5-353): 5.06e-39: 150: 14.21
+	Hs
		906447 PP1B_HUMAN (1-330): 0: 568: 87.88		ASPP2_HUMAN (5-353): 5.06e-39: 150: 14.21
+	Dm
		819225 PP11_DROME (4-330): 0: 573: 87.77		Q9VBP2_DROME (8-88): 4.69e-30: 122: 56.79