Protein: M4K4
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)

Gene: M4K4, Map4k4
Organism: Mus musculus
Interactions: 20
UniProt ID: P97820

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

949264

TNIK
Traf2 and NCK-interacting protein kinase

1

17

High-throughput

0.691

High

956960

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

17

High-throughput

0.691

High

682106

AKT1
RAC-alpha serine/threonine-protein kinase

1

17

Small-scale

0.618

High

956961

AKT2
RAC-beta serine/threonine-protein kinase

1

20

Small-scale

0.618

High

956972

AKT3
RAC-gamma serine/threonine-protein kinase

1

17

Small-scale

0.618

High

956967

PTK7
Inactive tyrosine-protein kinase 7

1

20

High-throughput

0.553

High

956969

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.553

High

956962

FXR1
RNA-binding protein FXR1

1

9

High-throughput

0.536

High

956966

MYOME
Myomegalin

1

20

High-throughput

0.536

High

956963

CE290
Centrosomal protein of 290 kDa

1

20

High-throughput

0.489

High

956965

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

7

High-throughput

0.489

High

956971

DLGP1
Disks large-associated protein 1

1

2

High-throughput

0.489

High

956959

STING
Stimulator of interferon genes protein

1

4

High-throughput

0.479

High

868922

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

956964

TEDC2
Tubulin epsilon and delta complex protein 2

1

0

High-throughput

0.458

High

729456

FMR1
Fragile X messenger ribonucleoprotein 1

1

9

High-throughput

0.445

High

102988

G3X9H5
Huntingtin

1

3

High-throughput

0.437

High

371805

CFAD
Complement factor D

1

3

High-throughput

0.437

High

956968

Q8BPK8
Agenet-like domain-containing protein

1

9

High-throughput

0.437

High

956970

NCK1
SH2/SH3 adapter protein Nck1

1

20

High-throughput

0.417

High


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Last updated: 15 Jul 2024