HitPredict

Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: SFRP1 (Q8N474)
Secreted frizzled-related protein 1 (FRP-1) (sFRP-1) (Secreted apoptosis-related protein 2) (SARP-2)
Gene: SFRP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	17123353, 21382349
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 314
+	Hs
		737920 PP1G_HUMAN (1-330): 0: 579: 90.66		SFRP1_HUMAN (1-314): 3.07e-124: 359: 100.00
+	Hs
		906532 PP1B_HUMAN (1-330): 0: 568: 87.88		SFRP1_HUMAN (1-314): 3.07e-124: 359: 100.00
+	Hs
		905956 PP1A_HUMAN (1-330): 0: 614: 100.00		SFRP5_HUMAN (29-313): 4.32e-105: 311: 55.75
+	Hs
		906078 PP1A_HUMAN (1-330): 0: 614: 100.00		SFRP2_HUMAN (51-306): 4.51e-93: 280: 42.59
+	Hs
		737855 PP1G_HUMAN (1-330): 0: 579: 90.66		SFRP5_HUMAN (29-313): 4.32e-105: 311: 55.75
+	Hs
		906488 PP1B_HUMAN (1-330): 0: 568: 87.88		SFRP5_HUMAN (29-313): 4.32e-105: 311: 55.75
+	Hs
		737974 PP1G_HUMAN (1-330): 0: 579: 90.66		SFRP2_HUMAN (51-306): 4.51e-93: 280: 42.59
+	Hs
		906559 PP1B_HUMAN (1-330): 0: 568: 87.88		SFRP2_HUMAN (51-306): 4.51e-93: 280: 42.59