HitPredict

Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	28330616, 29669786, 35271311, 17643375
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 463
+	Mm
		906384 PP1A_MOUSE (1-330): 0: 614: 99.70		RUVB2_MOUSE (1-463): 0: 718: 99.57
+	Hs
		738134 PP1G_HUMAN (1-330): 0: 579: 90.66		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Mm
		888047 PP1A_MOUSE (1-330): 0: 614: 99.70		RUVB1_MOUSE (8-451): 0: 656: 42.67
+	Hs
		906206 PP1A_HUMAN (1-330): 0: 614: 100.00		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Hs
		738135 PP1G_HUMAN (1-330): 0: 579: 90.66		RUVB1_HUMAN (8-451): 0: 655: 42.67