HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007049 - cell cycle GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 1117
+	Hs
		737866 PP1G_HUMAN (1-327): 0: 569: 86.89		CYTSA_HUMAN (1-1117): 1.12e-71: 262: 100.00
+	Hs
		906486 PP1B_HUMAN (1-327): 0: 597: 100.00		CYTSB_HUMAN (167-1117): 3.95e-60: 226: 38.76
+	Dm
		54320 Q8T0U6_DROME (18-322): 0: 550: 91.48		A1Z9J3_DROME (870-1115): 1.47e-70: 262: 25.10
+	Hs
		737849 PP1G_HUMAN (1-327): 0: 569: 86.89		CYTSB_HUMAN (167-1117): 3.95e-60: 226: 38.76
+	Hs
		521519 PP1B_HUMAN (1-327): 0: 597: 100.00		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Hs
		725638 PP1B_HUMAN (1-327): 0: 597: 100.00		ACTN2_HUMAN (1009-1115): 3.7e-48: 188: 41.67
+	Hs
		211552 PP1B_HUMAN (1-327): 0: 597: 100.00		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		724747 PP1B_HUMAN (1-327): 0: 597: 100.00		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		905938 PP1A_HUMAN (1-326): 0: 576: 88.79		SMTL2_HUMAN (663-1116): 1.6e-41: 161: 17.46
+	Hs
		724746 PP1A_HUMAN (1-326): 0: 576: 88.79		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		930877 PP2AA_HUMAN (8-303): 2.77e-176: 491: 45.79		CYTSB_HUMAN (167-1117): 3.95e-60: 226: 38.76
+	Hs
		724689 PP1G_HUMAN (1-327): 0: 569: 86.89		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Mm
		906240 PP1A_MOUSE (1-326): 0: 576: 88.49		MYH6_MOUSE (213-1085): 1.09e-30: 133: 12.76
+	Hs
		528366 PP1A_HUMAN (1-326): 0: 576: 88.79		MYH6_HUMAN (213-1085): 2.74e-30: 132: 12.64
+	Dm
		404229 PP1B_DROME (1-322): 0: 568: 90.37		MYSA_DROME (9-775): 1.21e-27: 123: 9.63
+	Dm
		819289 PP1B_DROME (1-322): 0: 568: 90.37		MYSN_DROME (348-1092): 6.68e-23: 108: 12.32
+	Dm
		404244 Q8T0U6_DROME (18-322): 0: 550: 91.48		MYSA_DROME (9-775): 1.21e-27: 123: 9.63
+	Hs
		724764 PP2AA_HUMAN (8-303): 2.77e-176: 491: 45.79		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		725131 PP2AB_HUMAN (8-303): 1.26e-176: 492: 46.13		MYH10_HUMAN (213-1075): 1.21e-33: 143: 10.62