HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: UACA (Q9BZF9)
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene: UACA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	26496610, 28330616
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 1416
+	Hs
		906005 PP1A_HUMAN (1-326): 0: 576: 88.79		MIB1_HUMAN (7-577): 1.39e-52: 203: 12.70
+	Hs
		738023 PP1G_HUMAN (1-327): 0: 569: 86.89		UACA_HUMAN (3-1323): 6.02e-45: 180: 14.97
+	Mm
		906317 PP1A_MOUSE (1-326): 0: 576: 88.49		UACA_MOUSE (3-1309): 1.12e-40: 166: 13.13
+	Hs
		528366 PP1A_HUMAN (1-326): 0: 576: 88.79		MYH6_HUMAN (260-1295): 1.21e-36: 153: 13.31
+	Hs
		906617 PP1B_HUMAN (1-327): 0: 597: 100.00		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Mm
		906240 PP1A_MOUSE (1-326): 0: 576: 88.49		MYH6_MOUSE (260-1281): 8.25e-33: 141: 13.33
+	Hs
		738091 PP1G_HUMAN (1-327): 0: 569: 86.89		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		862021 PP2AA_HUMAN (8-303): 2.77e-176: 491: 45.79		DAPK1_HUMAN (160-397): 1.88e-10: 67.9: 11.67