HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: WBP11 (Q9Y2W2)
WW domain-binding protein 11 (WBP-11) (Npw38-binding protein) (NpwBP) (SH3 domain-binding protein SNP70) (Splicing factor that interacts with PQBP-1 and PP1)
Gene: WBP11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 641
+	Mm
		906344 PP1A_MOUSE (1-326): 0: 576: 88.49		WBP11_MOUSE (1-641): 1.75e-82: 274: 95.16
+	Hs
		906210 PP1A_HUMAN (1-326): 0: 576: 88.79		WBP11_HUMAN (1-641): 2.71e-82: 273: 100.00
+	Mm
		926553 PP1G_MOUSE (1-327): 0: 569: 86.89		WBP11_MOUSE (1-641): 1.75e-82: 274: 95.16
+	Hs
		738139 PP1G_HUMAN (1-327): 0: 569: 86.89		WBP11_HUMAN (1-641): 2.71e-82: 273: 100.00
+	Hs
		90115 PP1A_HUMAN (1-326): 0: 576: 88.79		D6REX3_HUMAN (295-623): 9.1e-18: 89.8: 13.37
+	Dm
		113980 PP1B_DROME (1-322): 0: 568: 90.37		M9PB30_DROME (162-626): 8.11e-09: 61.3: 9.68