HitPredict

Interactor 1: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Interactor 2: PSMD5 (Q16401)
26S proteasome non-ATPase regulatory subunit 5 (26S protease subunit S5 basic) (26S proteasome subunit S5B)
Gene: PSMD5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, 19490896
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0022624 - proteasome accessory complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 504
+	Hs
		906840 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		PSMD5_HUMAN (1-504): 0: 694: 100.00
+	Hs
		798675 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		PSMD5_HUMAN (1-504): 0: 694: 100.00
+	Hs
		730271 PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31		PSMD5_HUMAN (1-504): 0: 694: 100.00
+	At
		1195595 PRS4A_ARATH (19-396): 1.25e-158: 455: 47.62		Q84M90_ARATH (65-493): 1.18e-157: 460: 21.59
+	Dm
		820531 PRS4_DROME (4-396): 3.02e-138: 403: 45.04		PSMD5_DROME (83-501): 8.48e-148: 434: 25.65
+	Dm
		1181062 Q7KMQ0_DROME (81-392): 1.77e-115: 345: 55.45		PSMD5_DROME (83-501): 8.48e-148: 434: 25.65
+	Hs
		913277 PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64		PSMD5_HUMAN (1-504): 0: 694: 100.00