Protein: LPAR6
Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor)

Gene: LPAR6
Organism: Homo sapiens
Interactions: 65
UniProt ID: P43657

Gene Ontology (top 5):
GO:0001835 - blastocyst hatching
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0043231 - intracellular membrane-bounded organelle
GO:0070915 - lysophosphatidic acid receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

316604

ST17B
Serine/threonine-protein kinase 17B

2

5

High-throughput

0.789

High

349390

TSN15
Tetraspanin-15

3

19

High-throughput

0.667

High

547419

DMD
Dystrophin

3

4

High-throughput

0.667

High

658656

JAK1
Tyrosine-protein kinase JAK1

3

20

High-throughput

0.667

High

658862

PTPRD
Receptor-type tyrosine-protein phosphatase delta

3

7

High-throughput

0.667

High

851057

CAV1
Caveolin-1

3

7

High-throughput

0.667

High

851064

LMBD2
G-protein coupled receptor-associated protein LMBRD2

3

8

High-throughput

0.667

High

851069

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

3

5

High-throughput

0.667

High

851081

ORAI1
Calcium release-activated calcium channel protein 1

3

1

High-throughput

0.667

High

851088

PKP2
Plakophilin-2

3

3

High-throughput

0.667

High

851089

HYCCI
Hyccin

3

2

High-throughput

0.667

High

851087

S38A2
Sodium-coupled neutral amino acid symporter 2

2

2

High-throughput

0.628

High

178617

DEGS1
Sphingolipid delta(4)-desaturase DES1

2

4

High-throughput

0.611

High

297169

PRAF3
PRA1 family protein 3

2

3

High-throughput

0.611

High

851055

AT8B2
Phospholipid-transporting ATPase ID

2

20

High-throughput

0.611

High

851078

CTR3
Cationic amino acid transporter 3

2

12

High-throughput

0.611

High

851082

VMP1
Vacuole membrane protein 1

2

2

High-throughput

0.611

High

851062

MTX3
Metaxin-3

3

9

High-throughput

0.609

High

851066

ATLA3
Atlastin-3

3

13

High-throughput

0.609

High

851075

SFXN5
Sideroflexin-5

3

7

High-throughput

0.609

High

851094

MITOS
Mitochondrial potassium channel ATP-binding subunit

3

6

High-throughput

0.609

High

851052

EMP1
Epithelial membrane protein 1

2

4

High-throughput

0.606

High

225364

ERD23
ER lumen protein-retaining receptor 3

2

8

High-throughput

0.558

High

397586

NU1M
NADH-ubiquinone oxidoreductase chain 1

2

2

High-throughput

0.558

High

851067

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

2

13

High-throughput

0.558

High

851068

MBOA5
Lysophospholipid acyltransferase 5

2

9

High-throughput

0.558

High

851070

BRAT1
Integrator complex assembly factor BRAT1

2

6

High-throughput

0.558

High

851074

ATLA2
Atlastin-2

2

13

High-throughput

0.558

High

851080

GCP3
Gamma-tubulin complex component 3

2

14

High-throughput

0.558

High

851085

ARL5B
ADP-ribosylation factor-like protein 5B

2

3

High-throughput

0.558

High

851095

IPO11
Importin-11

2

20

High-throughput

0.558

High

851096

T184B
Transmembrane protein 184B

2

1

High-throughput

0.558

High

851084

SC22A
Vesicle-trafficking protein SEC22a

2

3

High-throughput

0.553

High

851093

RPRM
Protein reprimo

2

2

High-throughput

0.553

High

333561

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

1

High-throughput

0.536

High

851083

AB17A
Alpha/beta hydrolase domain-containing protein 17A

1

10

High-throughput

0.536

High

851091

RTN4
Reticulon-4

1

8

High-throughput

0.536

High

156246

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

1

High-throughput

0.489

High

582077

PGAM2
Phosphoglycerate mutase 2

1

1

High-throughput

0.489

High

851053

HBB
Hemoglobin subunit beta

1

1

High-throughput

0.489

High

851054

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.489

High

851059

RAB32
Ras-related protein Rab-32

1

7

High-throughput

0.489

High

410702

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

19

High-throughput

0.479

High

714587

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

20

High-throughput

0.479

High

851051

KNTC1
Kinetochore-associated protein 1

1

5

High-throughput

0.479

High

851056

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

851058

ATM
Serine-protein kinase ATM

1

20

High-throughput

0.479

High

851071

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

3

High-throughput

0.479

High

851072

NLRX1
NLR family member X1

1

7

High-throughput

0.479

High

851073

ZDH17
Palmitoyltransferase ZDHHC17

1

9

High-throughput

0.479

High

851077

LMBR1
Limb region 1 protein homolog

1

3

High-throughput

0.479

High

851086

EXOC2
Exocyst complex component 2

1

11

High-throughput

0.479

High

129857

GET1
Guided entry of tail-anchored proteins factor 1

1

1

High-throughput

0.437

High

164546

TNPO2
Transportin-2

1

18

High-throughput

0.437

High

208030

TTI1
TELO2-interacting protein 1 homolog

1

5

High-throughput

0.437

High

506572

GPHRB
Golgi pH regulator B

1

10

High-throughput

0.437

High

851060

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

17

High-throughput

0.437

High

851061

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

7

High-throughput

0.437

High

851063

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

5

High-throughput

0.437

High

851065

INT3
Integrator complex subunit 3

1

1

High-throughput

0.437

High

851076

COG1
Conserved oligomeric Golgi complex subunit 1

1

4

High-throughput

0.437

High

851079

GLMN
Glomulin

1

3

High-throughput

0.437

High

249831

STX10
Syntaxin-10

3

0

High-throughput

0.347

High

851092

PXMP2
Peroxisomal membrane protein 2

2

0

High-throughput

0.318

High

851090

SMIM3
Small integral membrane protein 3

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025