Interactor 1: CLCN7 (P51798)
H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)
Gene: CLCN7
Interactor 2: OSTM1 (Q86WC4)
Osteopetrosis-associated transmembrane protein 1 (Chloride channel 7 beta subunit)
Gene: OSTM1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.90 | 1.00 | 0.949 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32851177, 33961781, 32749217, 35271311, 40437099, unassigned3799 |
| Identification Methods | pull down, affinity chromatography technology, x-ray crystallography, cross-linking study, anti tag coimmunoprecipitation, 3D electron microscopy |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | OSTMP1~Voltage_CLC |
| Common GO terms | GO:0005765 - lysosomal membrane GO:0030321 - transepithelial chloride transport GO:0034707 - chloride channel complex |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
