HitPredict

Interactor 1: CLCN7 (O70496)
H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)
Gene: CLCN7

Interactor 2: OSTM1 (Q8BGT0)
Osteopetrosis-associated transmembrane protein 1 (Chloride channel 7 beta subunit) (Grey-lethal protein)
Gene: OSTM1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 26598607, 16525474
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains OSTMP1~Voltage_CLC
Common GO terms GO:0005765 - lysosomal membrane
GO:0030321 - transepithelial chloride transport
GO:0034707 - chloride channel complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 803
Mm

1 338
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025