HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0045296 - cadherin binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1025
+	Mm
		910229 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MPRIP_MOUSE (1-1024): 9.38e-118: 388: 88.01
+	Hs
		909845 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		909680 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		910040 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		725130 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		728460 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57