HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	34079125, 35271311, 36931259, 17979178
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1356
+	Hs
		909853 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Dm
		955046 1433E_DROME (1-254): 2.95e-146: 411: 82.69		Q9VX75_DROME (1-1082): 3.49e-78: 286: 21.87
+	Dm
		954995 1433E_DROME (1-254): 2.95e-146: 411: 82.69		Q0KHR3_DROME (42-1082): 6.25e-62: 235: 20.76
+	Rn
		910361 1433E_RAT (1-255): 4.87e-154: 430: 100.00		RIMS1_RAT (314-947): 2.11e-50: 198: 17.14
+	Mm
		910260 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Hs
		909498 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50