HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: CNTLN (Q9NXG0)
Centlein (Centrosomal protein)
Gene: CNTLN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019904 - protein domain specific binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1405
+	Mm
		910250 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		GRDN_MOUSE (511-1377): 9.89e-30: 131: 15.58
+	Hs
		725130 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYH10_HUMAN (668-1405): 7.47e-26: 118: 9.04
+	Hs
		909975 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CP250_HUMAN (8-837): 1.09e-25: 118: 9.28
+	Hs
		728460 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYH11_HUMAN (901-1405): 3.14e-25: 116: 10.69
+	Hs
		909625 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		GRDN_HUMAN (600-1400): 6.26e-22: 105: 14.01
+	Mm
		93548 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		DESP_MOUSE (66-833): 2.07e-20: 100: 12.60
+	Zm
		5465 B6U284_MAIZE (3-255): 8.23e-147: 412: 70.59		A0A1D6DZK4_MAIZE (895-1403): 2.78e-17: 90.3: 10.29