HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: MTMR4 (Q9NYA4)
Myotubularin-related protein 4 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Zinc finger FYVE domain-containing protein 11)
Gene: MTMR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28675297, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0019903 - protein phosphatase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1195
+	Hs
		909535 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MTMR3_HUMAN (1-1195): 0: 1019: 47.63
+	Hs
		909534 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MTMR2_HUMAN (7-630): 0: 716: 32.77
+	Hs
		309464 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MTMR5_HUMAN (161-802): 8.65e-151: 499: 21.79
+	Hs
		910000 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		909717 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		909944 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00