HitPredict

Interactor 1: RUXE (P62304)
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)
Gene: SNRPE

Interactor 2: SMD3 (P62318)
Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3)
Gene: SNRPD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.863

The method score is based on:

Property Details
Experiments 9417867, 28514442, 33961781
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LSM~LSM
Common GO terms GO:0000387 - spliceosomal snRNP assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 21 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 92
Hs

1 126
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ At
+ Ce
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024