HitPredict

Interactor 1: RUXG (P62308)
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)
Gene: SNRPG

Interactor 2: SART3 (Q15020)
Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (Tat-interacting protein of 110 kDa) (Tip110) (p110 nuclear RNA-binding protein)
Gene: SART3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~Lsm_interact
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 76 Hs			1 963
+	Hs
		68420 RUXGL_HUMAN (1-76): 7.68e-29: 99.4: 94.74		SART3_HUMAN (1-963): 0: 638: 100.00
+	Hs
		912227 LSM6_HUMAN (3-75): 3.42e-27: 95.5: 26.03		SART3_HUMAN (1-963): 0: 638: 100.00
+	Hs
		1063305 LSM7_HUMAN (3-76): 1.74e-24: 89.4: 32.93		SART3_HUMAN (1-963): 0: 638: 100.00
+	Hs
		927951 RSMN_HUMAN (1-70): 1.26e-22: 88.2: 21.25		SART3_HUMAN (1-963): 0: 638: 100.00
+	Ce
		1088927 Q95XN6_CAEEL (1-72): 1.1e-27: 96.7: 33.78		SART3_CAEEL (73-962): 3.23e-124: 399: 24.26
+	Ce
		1088932 RUXG_CAEEL (1-76): 9.96e-27: 94.4: 65.79		SART3_CAEEL (73-962): 3.23e-124: 399: 24.26
+	Ce
		712466 RUXF_CAEEL (5-75): 3.88e-26: 92.8: 26.76		SART3_CAEEL (73-962): 3.23e-124: 399: 24.26
+	Hs
		912106 RUXG_HUMAN (1-76): 1.78e-29: 100: 100.00		CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35
+	Hs
		68456 RUXGL_HUMAN (1-76): 7.68e-29: 99.4: 94.74		CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35
+	Hs
		928016 RSMN_HUMAN (1-70): 1.26e-22: 88.2: 21.25		CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35
+	Hs
		300100 RUXG_HUMAN (1-76): 1.78e-29: 100: 100.00		PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10
+	Hs
		68390 RUXGL_HUMAN (1-76): 7.68e-29: 99.4: 94.74		PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10
+	Hs
		300102 LSM6_HUMAN (3-75): 3.42e-27: 95.5: 26.03		PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10
+	Hs
		300284 LSM7_HUMAN (3-76): 1.74e-24: 89.4: 32.93		PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10
+	Hs
		300110 RSMN_HUMAN (1-70): 1.26e-22: 88.2: 21.25		PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10
+	Hs
		912115 RUXG_HUMAN (1-76): 1.78e-29: 100: 100.00		SYF1_HUMAN (34-365): 2.09e-14: 79.7: 12.39
+	Hs
		68460 RUXGL_HUMAN (1-76): 7.68e-29: 99.4: 94.74		SYF1_HUMAN (34-365): 2.09e-14: 79.7: 12.39
+	Dm
		1376453 Q9W2P5_DROME (1-75): 1.23e-25: 91.7: 24.68		RNP4F_DROME (791-895): 5.63e-16: 85.1: 40.00
+	Sp
		252597 RUXG_SCHPO (1-76): 1.27e-24: 89: 47.37		PRP1_SCHPO (35-363): 5.2e-15: 82: 11.64
+	Hs
		928028 RSMN_HUMAN (1-70): 1.26e-22: 88.2: 21.25		SYF1_HUMAN (34-365): 2.09e-14: 79.7: 12.39