Protein: RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (ABC14.4) (ABC14.5) (DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide)

Gene: RPAB3, RPB8
Organism: Saccharomyces cerevisiae S288C
Interactions: 111
UniProt ID: P20436

Gene Ontology (top 5):
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594178

RPB3
DNA-directed RNA polymerase II subunit RPB3

19

4

Small-scale

0.985

High

401882

RPB1
DNA-directed RNA polymerase II subunit RPB1

13

10

Small-scale

0.975

High

534213

RPA1
DNA-directed RNA polymerase I subunit RPA190

6

10

Small-scale

0.943

High

632341

RPB11
DNA-directed RNA polymerase II subunit RPB11

6

3

Small-scale

0.933

High

402190

RPC1
DNA-directed RNA polymerase III subunit RPC1

5

10

Small-scale

0.921

High

459016

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

4

4

Small-scale

0.904

High

632123

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

11

1

Small-scale

0.752

High

632332

RPB7
DNA-directed RNA polymerase II subunit RPB7

9

5

Small-scale

0.749

High

632314

RPB9
DNA-directed RNA polymerase II subunit RPB9

8

5

Small-scale

0.743

High

470459

RPB2
DNA-directed RNA polymerase II subunit RPB2

7

6

Small-scale

0.742

High

632057

RPB4
DNA-directed RNA polymerase II subunit RPB4

7

1

Small-scale

0.739

High

632303

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

5

1

Small-scale

0.706

High

632304

RPC2
DNA-directed RNA polymerase III subunit RPC2

5

6

Small-scale

0.706

High

632225

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

5

3

Small-scale

0.702

High

632348

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

4

1

Small-scale

0.676

High

632329

RPC6
DNA-directed RNA polymerase III subunit RPC6

3

1

Small-scale

0.676

High

632322

RPA12
DNA-directed RNA polymerase I subunit RPA12

3

5

High-throughput

0.662

High

632320

RPC3
DNA-directed RNA polymerase III subunit RPC3

3

1

High-throughput

0.656

High

632344

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

3

1

Small-scale

0.656

High

632352

T2FB
Transcription initiation factor IIF subunit beta

3

1

Small-scale

0.656

High

632308

RPC4
DNA-directed RNA polymerase III subunit RPC4

3

0

High-throughput

0.634

High

632354

RPA43
DNA-directed RNA polymerase I subunit RPA43

3

0

Small-scale

0.628

High

632378

IWR1
RNA polymerase II nuclear localization protein IWR1

3

0

Small-scale

0.628

High

632334

RPC8
DNA-directed RNA polymerase III subunit RPC8

2

5

High-throughput

0.621

High

632343

RSP5
E3 ubiquitin-protein ligase RSP5

2

3

High-throughput

0.619

High

632315

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

3

High-throughput

0.618

High

632377

ASR1
Alcohol-sensitive RING finger protein 1

3

0

Small-scale

0.613

High

632302

RPA2
DNA-directed RNA polymerase I subunit RPA135

2

6

High-throughput

0.611

High

632365

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

1

High-throughput

0.601

High

632383

CMR1
DNA damage-binding protein CMR1

2

1

High-throughput

0.586

High

632313

SPT5
Transcription elongation factor SPT5

2

3

High-throughput

0.584

High

632358

GPN1
GPN-loop GTPase 1

3

3

Small-scale

0.576

High

632357

RPC9
DNA-directed RNA polymerase III subunit RPC9

2

0

Small-scale

0.569

High

632349

ULP2
Ubiquitin-like-specific protease 2

2

0

High-throughput

0.561

High

632330

SPT4
Transcription elongation factor SPT4

2

0

High-throughput

0.559

High

632333

TAF14
Transcription initiation factor TFIID subunit 14

2

0

Small-scale

0.559

High

632355

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

2

0

Small-scale

0.559

High

441327

KAPB
cAMP-dependent protein kinase type 2

1

1

High-throughput

0.536

High

632339

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.501

High

632346

RAD26
DNA repair and recombination protein RAD26

1

1

Small-scale

0.501

High

632301

MCK1
Protein kinase MCK1

1

0

High-throughput

0.480

High

632331

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.480

High

380959

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381394

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

381864

H4
Histone H4

1

1

High-throughput

0.479

High

632305

SPT6
Transcription elongation factor SPT6

1

1

High-throughput

0.479

High

632316

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

632317

TF3B
Transcription factor IIIB 70 kDa subunit

1

3

High-throughput

0.479

High

632337

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

2

High-throughput

0.479

High

632338

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

632366

MCE1
mRNA-capping enzyme subunit alpha

1

1

High-throughput

0.479

High

632368

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

632369

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

5

High-throughput

0.479

High

624864

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

Small-scale

0.460

High

632347

NUP82
Nucleoporin NUP82

1

0

Small-scale

0.460

High

609174

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

0

High-throughput

0.458

High

632309

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

632310

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

632311

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.458

High

632312

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

632318

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

632319

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

632321

SP110
Spindle pole body component 110

1

0

High-throughput

0.458

High

632323

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

632325

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

Small-scale

0.458

High

632326

RAD23
UV excision repair protein RAD23

1

0

High-throughput

0.458

High

632327

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

632350

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

632351

T2FA
Transcription initiation factor IIF subunit alpha

1

0

High-throughput

0.458

High

632353

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

632356

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

632360

RPA14
DNA-directed RNA polymerase I subunit RPA14

1

0

High-throughput

0.458

High

632362

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

632363

H3
Histone H3

1

0

Small-scale

0.458

High

632364

SEN1
Helicase SEN1

1

0

High-throughput

0.458

High

632371

POB3
FACT complex subunit POB3

1

0

High-throughput

0.458

High

632373

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

632374

IWS1
Transcription factor SPN1

1

0

High-throughput

0.458

High

632376

CDC73
Cell division control protein 73

1

0

High-throughput

0.458

High

632379

SGO1
Shugoshin

1

0

High-throughput

0.458

High

632382

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.458

High

523027

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

525896

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

543784

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

632345

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

632375

GPN3
GPN-loop GTPase 3

1

3

Small-scale

0.437

High

632324

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.426

High

632336

LHS1
Heat shock protein 70 homolog LHS1

1

2

High-throughput

0.407

High

632381

YP225
Protein PBDC1 homolog

1

0

High-throughput

0.269

Low

560648

KIN2
Serine/threonine-protein kinase KIN2

1

0

High-throughput

0.261

Low

632307

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

0

High-throughput

0.261

Low

632361

NNF2
Protein NNF2

1

0

Small-scale

0.251

Low

148859

CET1
mRNA-capping enzyme subunit beta

1

0

Small-scale

0.249

Low

383513

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

433441

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

435766

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

454868

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

502844

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504033

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

512812

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514450

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

632328

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

632335

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

632340

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

632342

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

632359

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

632367

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

632370

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

632372

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low

632380

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

632306

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025